RESUMEN
Objective To observe the therapeutic effect of Qizhi Tongluo capsule on patients with apoplexy sequelae accompanied by qi deficiency and blood stasis. Methods Seventy-four patients with apoplexy sequelae accompanied by qi deficiency and blood stasis syndrome admitted to the Department of Traditional Chinese Medicine of Guangxi Zhuang Autonomous Region National Hospital From October 2014 to October 2017 were enrolled, they were randomly divided into a control group (36 cases) and an observation group (38 cases). Both groups were treated with acupuncture and moxibustion, intravenous drip of Xuesaitong and kept on a diet light, in control group, additionally Buyang Huanwu decoction (the ingredients: astragalus 50 g, angelica sinensis 12 g, allolobophora caliginosa trapezoides 10 g, peach kernel 10 g, szechwan lovage Rhizome 10 g, safflower 8 g, radix paeoniae rubra 10 g) was given, 1 dose daily, 1/2 dose being orally taken in the morning and 1/2 dose in the evening for consecutive 2 months: in the observation group, Qizhi Tongluo capsule 2 g was added, 2 times a day for consecutive 2 months. The differences in nerve function deficit score (NDS), the levels of triglyceride (TG) and cholesterol levels between the two groups were compared, and clinical therapeutic effects of two groups were observed. Results There were no statistical significant differences in NDS score (26.2±3.5 vs. 26.5±3.4), TG (mmol/L: 3.7±0.4 vs. 3.8±0.3), cholesterol (mmol/L: 7.5±1.3 vs. 7.3±1.2) before treatment in both groups (all P > 0.05), after treatment, the above indexes were significantly lowered than those before treatment, and the degrees of decrease after treatment in the observation group were more significant than those in the control group [NDS score: 12.6±2.8 vs. 20.7±2.8, TG (mmol/L): 1.1±0.2 vs. 1.9±0.3, cholesterol (mmol/L):4.8±1.2 vs. 5.7±1.1, all P < 0.05]; the total therapeutic effective rate in the observation group was significantly higher than that in the control group [94.7% (36/38) vs. 80.6% (29/36), P < 0.05]. Conclusion Qizhi Tongluo capsule can improve the clinical efficacy and effectively reduce the degree of nerve function defect in patients with apoplectic sequelae accompanied by qi deficiency and blood stasis syndrome.