Research progress on pancreatic hepatoid carcinoma / 中华肝胆外科杂志

Pancreatic hepatoid carcinoma (PHC) is a rare neoplasm that shares differentiation features with hepatocellular carcinoma. It is a special type of adenocarcinoma which can be accompanied by elevated serum AFP. PHC is highly invasive, and has a poor prognosis, and it usually present with vascular invasion, liver and/or lymph node metastasis. Preoperative diagnosis of PHC is difficult, and there is currently no consensus on its diagnosis and treatment. A better understanding of PHC is helpful to improve its diagnostic rate and to allow timely and effective application of treatment. This article reviews the research progress on PHC.