Comparison of pericapsular nerve group block and fascia iliaca compartment block for analgesia following hip fracture surgery: a meta-analysis / 中华麻醉学杂志

Objective:To systematically compare the analgesic efficacy of pericapsular nerve group (PENG) block and fascia iliaca compartment block (FICB) after hip fracture surgery.Methods:Databases including Pubmed, Embase, Cochrane, CNKI, Wanfang and VIP were searched for randomized controlled trials involving comparison of the analgesic efficacy of PENG block and FICB after hip fracture surgery from inception to August 2022. The primary outcome was the postoperative pain score, and the secondary outcome was the amount of postoperative analgesics and incidence of postoperative adverse reactions. The data were analyzed using Revman 5.4 software.Results:Eight studies were included ( n=374), and the pain score at rest 30 min after block was significantly lower in PENG group than in FICB group ( MD=-0.35, 95% CI -0.60--0.11, I2=14%, P<0.05). There was no statistically significant difference between PENG group and FICB group in pain scores at rest and during activity at 6, 12, 24 and 48 h after operation ( P>0.05). Compared with FICB group, the amount of analgesics used was significantly reduced at 24 and 48 h after operation in PENG group ( MD=-9.10, 95% CI -19.11-0.91, I2=95%, P<0.05). There was no statistically significant difference in the incidence of adverse reactions after operation between the two groups ( P>0.05). Conclusions:PENG block provides better efficacy when used for analgesia following hip fracture than FICB.

Applicability of the Institute of Medicine recommendations of gestational weight gain in women with twin pregnancies in Chengdu city / 中华健康管理学杂志

Objective:To analyze the applicability of the Institute of Medicine (IOM) recommendations of gestational weight gain (GWG) in women with twin pregnancies in Chengdu city.Methods:A total of 1 862 women delivering live twins ≥28 weeks of gestation at all midwifery institutions in Chengdu city from January 2013 to December 2019 were selected, and the women were divided into low GWG group (880 women), adequate GWG group (839 women) and excessive GWG group (143 women) according to the IOM recommendations of GWG. Information of the subjects was extracted from Chengdu “One-Card” Maternal and Child Health Information System. Chi-square test and analysis of variance were used to compare the basic information, pregnancy complications and perinatal adverse outcomes among the three groups. Multivariate logistic regression was used to analyze the relationship between GWG and pregnancy complications or perinatal adverse outcomes.Results:Of the women, 72.8% (611/1 862) had normal weight before pregnancy. The weight gain of low, adequate and excessive GWG groups was (11.8±3.4) kg, (18.8±2.6) kg and (26.1±2.9) kg, respectively. The incidence of low birthweight was highest in the low GWG group (71.0%), it was lowest in the excessive GWG group (51.0%), and it was 61.3% in the adequate GWG group ( P<0.001). There was no significant difference in gestational hypertension, gestational diabetes mellitus, premature rupture of membranes, very low birthweight, preterm birth, very premature birth, 5-minute Apgar score<7 and neonatal death within 7 days postpartum among the three groups (all P>0.05). The multivariable logistic regression analysis showed that, compared with women inadequate GWG group, those from the low GWG group tended to deliver infants with low birthweight ( OR=1.62, 95% CI: 1.32-2.00), whereas women from the excessive GWG group were less likely to deliver low birthweight infants ( OR=0.63, 95% CI: 0.44-0.91) (both P<0.05). Conclusion:The IOM recommendations for gestational weight gain are valuable in improving the pregnancy complications and perinatal outcomes of twin pregnancies in Chengdu city to certain extent, especially in improving the low birthweight of newborns.

Application of modified early warning score automatic disease early warning system combined with situation, background, assessment and recommen-dation in early warning of disease / 中国实用护理杂志

Objective@#To develop an automatic warning software system for MEWS, and apply the MEWS system and SBAR communication mode to the early warning of surgical patients to evaluate its implementation effect.@*Methods@#From November 2017 to November 2018, 400 patients in the People′s Hospital of Guigang City, Guangxi, with vital signs and critical illness after surgery were divided into 200 patients in the control group and 200 in the study group according to the random number table. The control group: routinely calculated MEWS scores and reported abnormal values to the doctor to treat the patient′s condition. The research group: Combining MEWS assignment with computer technology, developing MEWS automatic disease warning software system and combining it with SBAR communication mode for early warning of surgical patients′ condition, comparing the two groups′ disease evaluation time, treatment response speed, communication completion rate and Whether patients and doctors have different job satisfaction with nurses.@*Results@#The disease assessment time and treatment response rate of the study group were (45.89±1.528) seconds and (1.22±0.57) minutes, respectively. The control group was (58.01±5.123) seconds and (3.19±1.56) minutes respectively. The difference between the two groups was significant (t=32.078, -7.899, P<0.01). The communication completion rate of the study group, the patient's job satisfaction to the nurses, and the doctor's job satisfaction to the nurses was 96.0% (192/200), 91.5% (183/200) and 97.0% (194/200) respectively. The rate in the control group was 61.5% (123/200), 79.0% (158/200), and 78.0% (156/200) respectively, the difference between the two groups was significant (χ2=71.126, 12.426, 33.006, P < 0.01).@*Conclusion@#The MEWS automatic warning software system and SBAR communication mode can be used to quickly assess the patient′s condition, improve the accuracy of medical communication, alert patients to potential risks and severity of illness, and improve nurses' work efficiency and patient and doctor's satisfaction with nurses' work degree.

A novel tissue engineering complex——BMSCs Sheet-RADA16 scaffold constructed by cell sheet and self-assembled peptides technique / 实用口腔医学杂志

Objective: To construct a novel tissue engineering complex, BMSCs sheet-RADA16 scaffold, by combining cell sheet and self-assembled peptides.. Methods: The self-assembled peptide RADA16 scaffold was wrapped with the BMSCs cell sheet. The morphology of the cells and the complex were observed by SEM and confocal laser microscopy, and the proliferation of cells was assessed by CCK-8. The osteogenic differentiation of BMSCs was examined by detection of related gene expression with RT-PCR. Results: Compared with the BMSCs cell sheet, the numbers of cells on RADA16 scaffold growth rapidly at 3 rd-8 th day, and BMSCs were more on the scaffold than those on the cell sheet (P＜0. 05) . RT-PCR results showed that the expression level of osteogenesis-related genes was higher in the complex (P＜0. 05) . Conclusion: BMSCs Sheet-RADA16 Scaffold may promote proliferation and osteogenic differentiation of BMSCs.

Application of modified early warning score automatic disease early warning system combined with situation, background, assessment and recommen-dation in early warning of disease / 中国实用护理杂志

Objective To develop an automatic warning software system for MEWS, and apply the MEWS system and SBAR communication mode to the early warning of surgical patients to evaluate its implementation effect. Methods From November 2017 to November 2018, 400 patients in the People′s Hospital of Guigang City, Guangxi, with vital signs and critical illness after surgery were divided into 200 patients in the control group and 200 in the study group according to the random number table. The control group: routinely calculated MEWS scores and reported abnormal values to the doctor to treat the patient′s condition. The research group: Combining MEWS assignment with computer technology, developing MEWS automatic disease warning software system and combining it with SBAR communication mode for early warning of surgical patients′condition, comparing the two groups′disease evaluation time, treatment response speed, communication completion rate and Whether patients and doctors have different job satisfaction with nurses. Results The disease assessment time and treatment response rate of the study group were (45.89±1.528) seconds and (1.22±0.57) minutes, respectively. The control group was (58.01± 5.123) seconds and (3.19 ± 1.56) minutes respectively. The difference between the two groups was significant (t=32.078,-7.899, P<0.01). The communication completion rate of the study group, the patient's job satisfaction to the nurses, and the doctor's job satisfaction to the nurses was 96.0% (192/200), 91.5% (183/200) and 97.0% (194/200) respectively. The rate in the control group was 61.5% (123/200), 79.0% (158/200), and 78.0% (156/200) respectively, the difference between the two groups was significant (χ2=71.126, 12.426, 33.006, P < 0.01). Conclusion The MEWS automatic warning software system and SBAR communication mode can be used to quickly assess the patient′s condition, improve the accuracy of medical communication, alert patients to potential risks and severity of illness, and improve nurses'work efficiency and patient and doctor's satisfaction with nurses'work degree.

Factors associated with maternal health service in Chengdu China / 中华健康管理学杂志

Objective To investigate the status and associated factors with maternal health service in Chengdu China.Methods A cross-sectional survey was conducted in Chengdu between September to December in 2016;1 000 delivery women were recruited to finish the questionnaire and informed consents were obtained by investigators face to face.Cluster random sampling was adopted to select subjects from public health centers of different townships in Chengdu.The multivariate logistic regression model was used to analyze the associated factors with maternal health service.Results The record rate of early pregnancy,the postpartum visit rate and the maternal system management rate were 88.9％,90.4％ and 78.6％ respectively.The survey rates were significantly lower than the reported rates (x2=6.28,P＜0.01).The attitude of medical staff (OR=2.16,95％ CI:1.0d-4.48),perceived making the record of the first trimester of pregnancy (OR=2.88,95％ CI:1.03-8.14),pregnant women receiving maternal knowledge through doctors (OR=0.29,95％CI:0.13-0.64),through social activities (OR=0.40,95％CI:0.23-0.70),through advertisements (OR=3.42,95％ CI:1.54-7.58),from internet (OR=1.71,95％ CI:1.08-2.71) and from newspapers and magazines (OR=3.80,95％ CI:1.30-11.11) were associated with record filing during early pregnancy.Delivery women who were in the maternal age between 31 to 35 (OR=0.26,95％CI:0.08-0.87) and choosing hospitals close to home is the determinant of prenatal examination (OR=0.51,95％ 6I:0.31-0.82) were less likely to accept the postpartum visit.Delivery women who chose district hospitals(OR=3.21,95％ CI:1.26-8.19),provincial (OR=4.33,95％ CI:1.72-10.91) and municipal (OR=4.24,95％CI:1.38-12.99) maternal and child care service centers to do prenatal examination were more likely to receive the postpartum visit.The attitude of medical staff (OR=1.69,95％ CI:1.04-2.73),perceived making the record of the first trimester of pregnancy (OR=2.58,95％CI:1.04-6.42),pregnant women getting maternal knowledge by internet (OR=1.63,95％ CI:1.20-2.23),Delivery women who chose township health center (OR=6.60,95％ CI:1.27-34.48),provincial (OR=2.40,95％CI:1.07-5.39) and municipal (OR=3.72,95％CI:1.41-9.79)maternal and child care service centers to receive prenatal examinations might affect the maternal system management.Conclusion The maternal system management rate was low and there was significant difference between the survey rates and the reported rates.The attitude of medical staff,the channel of getting maternal knowledge and the choices of hospitals for receiving prenatal examinations affected the maternal health service.

Diagnostic value of MSCT in cystic nephroma / 实用放射学杂志

Objective To discuss the diagnostic performance of MSCT in cystic nephroma(CN).Methods The MSCT findings of CN in 7 patients proved by operation and pathology were retrospectively reviewed.Results All of 7 cases were isolated cystic lesion, including 5 males and 2 females.MSCT scanning showed cystic tumor in the renal parenchyma with well-defined boundary.All cases showed regular cystic wall and septa with no attached cystic wall nodule.The cystic wall and septa appeared homogeneous enhancement on contrast-enhanced CT,while the cystic space showed inhomogeneous density and lack of enhancement.Conclusion The MSCT findings of CN may benefit the definite diagnosis.

Study on detection value of noninvasive cerebral hemodynamics and serum nerve function indexes in patients with craniocerebral injury / 国际检验医学杂志

Objective To study and investigate the detection value of noninvasive cerebral hemodynamics and serum nerve func‐tion indexes in the patients with craniocerebral injury .Methods Totally 64 patients with craniocerebral injury in our hospital from September 2013 to May 2015 were selected as the observation group ,meanwhile 64 healthy persons with the same age were selected as the control group .Then the noninvasive cerebral hemodynamics and serum nerve function indexes were compared between the two groups ,furthermore the detection results in the observation group were compared among the patients with different severity de‐grees and intracranial pressures .Results The middle cerebral artery blood flow indexes of the observation group were all higher than those of the control group ,the serum nerve function indexes were also higher than those of the control group ,and the middle cerebral artery blood flow indexes and serum nerve function indexes of the observation group had obvious differences among the pa‐tients with different severity degrees and intracranial pressures too (P< 0 .05) ,showing statistical significance .Conclusion The noninvasive cerebral hemodynamics and serum nerve function indexes have highe detection value in the patients with craniocerebral injury ,and have active clinical role for the understand of disease severity degree and intracranial pressure situation .

Cognitive factors associated with the willingness for HIV testing among pregnant women in China / 中华医学杂志(英文版)

<p><b>BACKGROUND</b>The spread of human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) epidemic in the worldwide trend is not contained effectively. The pregnant women infected HIV seriously in the high HIV epidemic areas in China. The transmission of HIV to child may be cut off if HIV positive mother was found early by HIV testing. Pregnant women mandatorily received the HIV counseling and testing services. Most of them did not know the knowledge about HIV prevention and were not willing to receive HIV testing actively. Willingness for HIV testing among pregnant women was investigated, which can help to promote them to take up HIV testing actively. This study assessed the prevalence of the willingness for HIV testing and cognitive factors associated with it.</p><p><b>METHODS</b>A cross-sectional survey was conducted to 500 pregnant women via face-to-face interviews with anonymous structured questionnaire guided by the Health Belief Model (HBM).</p><p><b>RESULTS</b>The prevalence of the willingness for HIV testing was 58.60%. Perceived higher susceptibility to HIV (multivariate-adjusted odds ratio (ORm) = 2.02, 95% confidence interval (CI): 1.40-5.06), more knowledge for HIV (ORm = 1.92, 95% CI: 1.11-3.87) and perceived less social stigma (ORm = 0.80, 95% CI: 0.34-0.91) were associated with higher willingness for HIV testing among pregnant women.</p><p><b>CONCLUSION</b>To prevent HIV mother to children transmission, it is necessary to enhance knowledge for HIV, change cognitive factors and increase willingness for HIV testing among pregnant women.</p>

Analysis of the features of CT plan and enhanced scan of retroperitoneal ganglioneuroma / 中国基层医药

Objective To investigate the retroperitoneal ganglioneuroma ( GN) imaging findings ,and analyze its enhanced features .Methods 37 patients with retroperitoneal GN confirmed by pathology were chosen as subjects , the imaging features were analyzed and were compared with the pathologic results .All 37 cases underwent CT scan ,22 patients underwent CT enhance scan .Results 37 cases of retroperitoneal GN ,the lesions were located in the right side in 23 cases,14 cases located on the left.All lesions were demarcated,round or oval in 19 cases,18 cases of irreg-ular shape.CT scan 26 cases of 34 lesions of uniform density ,and density close to cystic lesions ,11 cases of 17 une-ven density,showed a little patchy,small strips calcification.Enhanced arterial phase lesions no enhancement ,venous phase and delayed phase showed progressive enhancement .Conclusion Retroperitoneal GN has certain characteristic imaging findings and strengthen the characteristics contribute to its diagnosis and differential diagnosis .

Diagnosis value comparison of 256-slice CT and 64-slice CT in pulmonary embolism / 中国基层医药

Objective To compare the value of 64-slice CT and 256-slice spiral CT in the diagnosis of pul-monary embolism.Methods A retrospective analysis CT pulmonary angiography of pulmonary embolism clinical cases,65 cases were in our hospital ,256-slice CT and 64-slice CT angiography were performed within 3 days of onset . The two kinds of inspection equipment for pulmonary embolism detection rate were analyzed and compared , and its image SNR, in contrast to noise ratio ,average scan time and the average dose of contrast agent used for comparison . Results The two devices display rate of pulmonary embolism was 100.0%,in the noise,image SNR,contrast to noise ratio,scan length,the 256-slice CT and 64-slice CT was no significant difference (P>0.05).The average 256-slice CT contrast agent was (4.45 ±1.37) mSv,64-slice CT was (5.68 ±1.06) mSv,there was significant difference between the two (t=2.77,P<0.05),an average of 256-slice CT scan time was (3.68 ±1.29)s,64-slice CT was (7.61 ± 1.40),there was significant difference between the two (t=11.33,P<0.001).Conclusion 256-slice CT and 64-slice CT can be used as an effective means of clinical diagnosis of pulmonary embolism ,but compared with 64-slice CT,the 256-slice CT can significantly reduce the scan time ,reduce the amount of radioactive contrast agent ,which has certain advantages .

Analysis on risk factors of stress urinary incontinence after vaginal delivery / 中国医师进修杂志

Objective To explore the risk factors of stress urinary incontinence (SUI) after vaginal delivery,and provide some clinical reference for its prophylaxis and treatment.Methods One hundred and nineteen patients had SUI after vaginal delivery (SUI group),and 217 patients had not SUI after vaginal delivery (control group).The relevant risk factors of SUI were analyzed by Logistic regression analysis.Results Single factor analysis results showed that age ≥ 30 years old,body mass index (BMI) ≥ 25 kg/m2,number of abortion ≥2 times,episiotomy,before or during pregnancy having urinary incontinence,postpartum increased abdominal pressure,history of constipation and neonatal weight in SUI group weresignificantly higher than those in control group [67.2％ (80/119) vs.39.6％ (86/217),65.5％ (78/119) vs.47.5％ (103/217),23.5％ (28/119) vs.13.4％ (29/217),31.1％ (37/119) vs.16.1％ (35/217),46.2％(55/119) vs.31.3％(68/217),28.6％(34/119) vs.15.2％(33/217),23.5％(28/119) vs.13.4％(29/217),(3.5 ± 0.4) kg vs.(3.2 ± 0.2) kg,P＜ 0.01 or ＜ 0.05].Multiplicity results showed that number of abortion ≥2 times,episiotomy,before or during pregnancy having urinary incontinence,postpartum increased abdominal pressure and high neonatal weight were independent risk factors of SUI (P ＜ 0.05).Conclusions Many abortion,episiotomy,before or during pregnancy having urinary incontinence,postpartum increased abdominal pressure and high neonatal weight are independent risk factors of SUI.Necessary intervention for the above risk factors has an important meaning,which may reduce the incidence of postpartum SUI.

Correlation study between human parvovirus B19 and spontaneous abortion / 中国医师进修杂志

Objective To investigate the correlation between human parvovirus (HPV) B19 and spontaneous abortion.Methods Participants included 30 cases of spontaneous abortion patients (patients group) and 30 normal pregnancy (control group).The potential risk of spontaneous abortion factors were recorded.Extracting all subjects cubits venous blood,HPV B19 DNA was tested by nested polymerase chain reaction,and HPV B19 IgM antibodies were determined by ELISA.The more factors analysis were performed by Logistic multiple regression analysis.Results There were significant differences in gravidity more than 2 times,combined with hypertension,combined with diabetes,HPV B19 DNA positive expression between patients group and control group [43.3％(13/30) vs.13.3％(4/30),33.3％(10/30) vs.6.7％(2/30),30.0％ (9/30) vs.6.7％ (2/30),36.7％ ( 11/30 ) vs.3.3％ ( 1/30)] (P ＜ 0.05 ).Logistic multiple regression analysis showed that gravidity more than 2 times,combined with hypertension,HPV B19 DNA positive expression were the independent risk factors of spontaneous abortion (OR =1.85,1.95,4.85,P ＜ 0.05).There was significant difference in the risk between early spontaneous abortion and lately spontaneous abortion in HPV B19 DNA positive expression patients (P ＜ 0.05 ).Conclusions HPV B19 infection is the natural abortion independent risk factors,need to early detection of pregnancy,and carry out necessary intervention in pregnant women,in order to reduce the occurrence of natural abortion.

Study on the HPLC fingerprints quality control of ascidian Styela plicata / 中国海洋药物

Objective To establish the HPLC fingerprints for the guality control of ascidian Styela plicata.Methods The HPLC fingerprints of ten batches of samples were obtained using ZORBAX Bonus-RP(4.6?250mm,5?m) column with a mix of acetonitrile and water with 0.01%TFA as mobile phase in a gradient mode,the detection wavelength was 254nm and the temperature was 30℃.Results The experiment and analysis were carried out on ten samples,the standard HPLC fingerprint pattern method and 13 characteristic diffraction peaks of Styela plicata were obtained.The proposed method was precise,reproducible and steady.Conclusion This reliable and convenient method can be used for the identification and quality control of Styela plicata.