The clinical value research of urine ferritin assay for the clinical diagnosis of cerebral infarction / 中国基层医药

Objective To study the clinical value of urine ferrite in assay for the clinical diagnosis of cerebral infarction.Methods 42 cases with cerebral infarction and 42 cases of health physical examination were regarded as the subjects of the observation group and the control group,respectively.The urine ferritin concentration and urinary creatinine were respectively assayed by the chemiluminescence method and enzyme method,and then calculated the urine ferritin creatinine ratio (TFR/Cr).Results Compared with the control group,the urine ferritin concentration [(60.0 ± 12.0)ng/mg · Cr vs (23.5 ±9.5) ng/mg · Cr,t =4.18)] and TFR/Cr[(15.0 ±4.6) μg/g vs (6.2 ±2.5)μg/g,t =3.86)] were significantly increased in the observation group with statistical difference (P ＜ 0.05).Conclusion The assay of urine ferritin creatinine ratio can provide the objective basis for clinical diagnosis of cerebral infarction,which is worthy of clinical promotion.

Influence of olanzapine combined with risperidone on the serum level of homocysteine in patients with schizophrenia / 中国基层医药

Objective To explore the influence of olanzapine combined with risperidone on the serum level of homocysteine (Hcy) in patients with schizophrenia.Methods Participants included sixty patients diagnosed with schizophrenia,patients were divided into two groups by means of random digital method.The group A was given olanzapine treatment,and the B group was given olanzapine combined with risperidone therapy.After two months follow-up,the curative effect and the level of Hcy were observed.Results Before treatment,Hcy level [(24.4 ± 6.1)μmol/L,(25.8 ± 7.7)μmol/L] and HH number (22 cases,23 cases) in the two groups had no obvious differences (t =1.11,x2 =1.34,all P ＞ 0.05) ;2 months after treatment,Hcy level (11.6 ± 8.6) μmol/L and HH number(16 cases) in group B were significantly lower than those in the group A [(16.3 ± 3.8) μmol/L,8 cases],the differences were statistically significant (t =4.65,x2 =4.32,all P ＜ 0.05).Conclusion Olanzapine combined with risperidone in treatment of schizophrenia have good curative effect,it can improve the symptoms of patients,decrease serum Hcy level and HH number.