RESUMEN
The silver colloid staining technique was used to count the number of Ag NORs associated protein in paraffin sections of chronic gastritis, gastric dysplasia and gastric adenocarcinoma. A significant difference in the mean number of Ag NORs per nucleus was found between: 1] control and gastric dysplasia or neoplasia, 2] chronic gastritis and gastric dysplasia or adenocarcinoma, 3] gastric dysplasia and gastric adenocarcinoma. However, there is no significant difference between control and chronic gastritis. These results indicate that this histochemical technique can be of value in diagnostic problems of borderline cases and have a role in the differentiation between chronic gastritis, gastric dysplasia and gastric adenocarcinoma
Asunto(s)
Neoplasias Gástricas , Región Organizadora del NucléoloRESUMEN
Silver colloid stain was used to count the number of A[g]NOR[s]- associated proteins in paraffin section of chronic cystitis, schistosomal cystitis and neoplastic lesions of urinary bladder. The mean number of AgNORs per nucleus is 1.7 in schistosmal cystitis, 2.9 in dysplasia, 3.0 in dysplasia wth schistosomal cystitis, 3.7 in squamous cell carcinoma, 4.9 in squamous cell carcinoma associated with schistosomal cystitis, 4.4 in transitional cell carcinoma and 6.0 in transitional cell carcinoma associated with schistosomal cystitis. It appears that there is a statistically significant different in the numbers of V: [1] Between chronic cystitis with or without schistomoisis and dysplastic lesions; [2] Between dysplastic lesions with or without schistosomiasis and malignant lesions; [3] Between cystitis with or without schistosomiasis and malignant lesions; [4] Between neoplasia associated with schistosomiasis and neoplasia in the absence of schistosomiasis. The results indicate that this histochemical technique can be of value in diagnostic problems of border line cases and may have a role in the differentiation between chronic cysttis, dysplasia and carcinoma of the bladdere