RESUMEN
Background: Renovascular hypertension and chronic kidney disease secondary to renal artery stenosis [RAS] can be treated by medical therapy, percutaneous transluminal angioplasty with or without stenting
Objective: To determine the effects of renal artery stenting on hypertension and renal function in patients with renal artery stenosis
Patients and Methods: This was an observational study in which 216 patients were identified retrospectively from 1[st] October, 2001 to 3T December 2006, who underwent 232 procedures. Clinical data pertaining to demographics, presence or absence of hypertension, creatinine, number of blood pressure medications and co morbidities was collected pre and post renal artery stenting, Follow up data was available for 144 procedures, with mean follow up period of 14 months
Results: In total, 232 procedures were performed on 216 patients, Of these, 95 [40.9%] had bilateral RAS [group 1], 117 [50.4%] had unilateral RAS [group 2], and 20 [8%] had RAS in a solitary functioning kidney [group 3]. Complete follow-up data was available on 144 patients. Indications for renal artery stenting were poorly controlled hypertension [56,9%], worsening renal function [8,6%], both [24.6%], and other [8,1%]. Procedural success was 100%, with no major in-lab complications. At a mean follow-up of 14.5 months, renal function remained stable with no significant difference in creatinine values but statistically significant drop in systolic blood pressure post stenting for the entire cohort and all the sub-groups
Conclusion: Renal artery stenting is a safe procedure with improvement of blood pressure control, stabilization or improvement in renal function in patients with unilateral, bilateral and RAS in solitary functioning kidneys