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Objective To discuss the value of multi-slice spiral CT angiography (MSCTA)and digital subtraction angiography (DSA)in lower extremity arteriosclerosis obliterans.Methods MSCTA and DSA of lower extremity arteries were performed in 41 patients with lower extremity arteriosclerosis obliterans sequentially.The interval of these two examinations was no more than 2 weeks.DSA served as the reference standard and compared with MSCTA in terms of grading of stenoocclusive lesions,visualization of collaterals in lower extremity arteries.Results No significant differences of grading of stenoocclusive lesions,visualization of col-laterals were observed between MCTA and DSA in lower extremity arteries.Compared with the results of DSA,the sensitivity,spe-cificity,accuracy,positive and negative predictive value of MSCTA in the detection of arterial stenosis (≥ 50%)were 97.2%, 98.2%,93.8%,94.6%,98.2%,respectively.Conclusion MSCTA shows relatively high sensitivity and specificity in the diagnosis of lower extremity arteriosclerosis obliterans,can provide effective guidance of planning treatment in lower extremity arteriosclerosis obliterans.
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Objective: To probe into the relationship between changes of sex hormone levels and TCM syndrome differentiation in climacteric women.Methods: According to TCM syndrome differentiation,55 cases of women in menopause were divided into three groups: kidney yang deficiency,kidney yin deficiency and the normal;the correlation between the three types and E2,FSH and LH was explored by statistical methods,and then they were compared with procreative women.Results: In all the 55 cases,kidney yin deficiency covered 70.90%,kidney yang deficiency covered 16.36%,the normal covered 12.72%;changes of E2 correlated positively with symptom scores of kidney yang deficiency and kidney yin deficiency;changes of FSH and LH correlate negatively with that of kidney yang deficiency and kidney yin deficiency.And they all correlated closely with menopause.Conclusion: the main syndrome type of climacteric women was kidney yin deficiency;E2↓,FSH↑ and LH↑ was expression of physiological kidney deficiency of climacteric women.
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Objective To investigate the effects of Xifeng Zhijing Capsul e on experimental Parkinson's disease(PD) in mice. Methods Mouse model of Parkin son's disease was established by intraperitoneal injection of 1- methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP) and mouse model of tremor was estab lished by intraperitoneal injection of oxygenated tremorine. Effects of Xifeng Z hijing Capsule on cerebral concentration of monoamine neurotransmitters such as dopamine (DA), 3, 4- dihydroxyphenylacetic acid (DOPAC), homovanillic acid (HVA) and its influence on the latency, duration and amplitude of tremor in th e extremities were observed. Results Xifeng Zhijing Capsule significantly incr eased the cerebral concentrations of DA, DOPAC and HVA in mice, and decreased the amplitude and duration of tremor in mice extremities. Conclusion Xifeng Z hijing Capsule has preventive and therapeutic effect for PD.