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0.05).(2) The transfection rate and velocity could be increased by addition of extra-magnetic field.(3) Transfected-p53 obviously inhibited the growth of HepG2 at G1 phase;the growth inhibition rate of HepG2 was 46%.Conclusions(1) FFN is a good vector for gene transfection,it can successfully transfect the gene into target cells.(2) Transefected-p53 can effectively inhibit the growth of HepG2.This result can establish a foundation for animal experimental research of gene therapy of malignancy.
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Objective To explore the value of CT in the preoperative assessment of resectability of advanced gastric carcinoma.Methods The relation of CT findings and operative data in 93 cases of advanced gastric carcinoma were retrospectively analyzed.Results There were 23 cases of fundus and cardia carcinoma,59 cases of carcinoma of gastric corpus,and 11 cases of carcinoma of antrum.All cases showed increased thickness of gastric wall in various degrees,some of the cases showed tumor growth in the gastric wall,ulcer of the mucosa,stricture of gastric cavity and cardia,increased thickness of cardiac wall,and invasion of lower esophagus and perigastric organs.The accuracy of location and definitive diagnosis by CT,compared to gastroscopic biopsy and postoperative pathology,was considerable,and the detecting rate of tumor by CT was 100 %.CT had important reference value in preoperative evaluation of tumor resectability.The excision rate in the predicted operable group was 93.3 %;in the predicted unresectable group,the non-excision rate was 75.0%.Conclusions Preoperative CT diagnosis of gastric carcinoma has important clinical significance.CT provides a high reference value for assessing the resectability of gastric carcinoma,and it is worthy of widespread use.