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1.
Indian J Cancer ; 2001 Jun-Dec; 38(2-4): 133-6
Artículo en Inglés | IMSEAR | ID: sea-50211

RESUMEN

Fibromatosis is a group of relatively uncommon benign diseases showing proliferation of fibrous tissues and is liable to be confused with fibrosarcoma, thereby causing diagnostic as well as therapeutic dilemmas. Even after the correct diagnosis is made, one is not sure about the most effective treatment is in a given setting. Surgery seems to provide the best results but is not feasible at many times due to the extent of the disease, hence the need for non-surgical modalities for unresectable and incompletely resected tumors. Mesenteric fibromatosis is one of the rarer forms of fibromatosis. Three such cases are being presented here with a brief review of the literature.


Asunto(s)
Adolescente , Adulto , Antineoplásicos Hormonales/uso terapéutico , Femenino , Fibromatosis Abdominal/tratamiento farmacológico , Humanos , Masculino , Mesenterio/patología , Tamoxifeno/uso terapéutico
2.
Artículo en Inglés | IMSEAR | ID: sea-64848

RESUMEN

Small cell carcinoma of the gall bladder is very rare. We report a 25-year-old woman with this tumor. These tumors typically occur in elderly women with cholelithiasis; chemotherapy is not known to improve survival.


Asunto(s)
Adulto , Carcinoma de Células Pequeñas/patología , Femenino , Neoplasias de la Vesícula Biliar/patología , Humanos
3.
Artículo en Inglés | IMSEAR | ID: sea-65137

RESUMEN

OBJECTIVE: To assess the success, complications and cost of endoscopic endoprosthesis placement for palliation of obstructive jaundice caused by malignancy. METHODS: Four hundred and two consecutive patients with obstructive jaundice due to nonresectable malignancy undergoing endoscopic stenting were studied. Commercial or home-made 7F or 10F endoprostheses were placed using minor modifications of the standard technique. The accessories were sterilized and reused. RESULTS: Endoprosthesis placement was successful in 291 patients (72.4%, 95% CI 67.7-76.7)-241 in one attempt, 49 in two attempts, and one in three attempts. Fifty nine patients (14.6%, 95% CI 11.4-18.6) had procedure-related complications, including cholangitis (30), pancreatitis (15), perforation (3) and bleeding (11). The incidence of cholangitis was significantly higher in bifurcation blocks than in other lesions (17.6% vs 4.7%, p = 0.0005). The success rate did not differ between distal and proximal lesions (68.1% vs 72.9%). The procedural cost per patient could be reduced from Rs 14,850 to Rs 6565 by reusing accessories after sterilization, and using home-made stents. CONCLUSIONS: Endoscopic endoprosthesis placement is a safe and effective method for palliation of malignant obstructive jaundice. Preparation of indigenous stents and reuse of accessories can reduce the cost of the procedure by over 50%.


Asunto(s)
Adulto , Anciano , Anciano de 80 o más Años , Colestasis/complicaciones , Análisis Costo-Beneficio , Endoscopía/efectos adversos , Femenino , Neoplasias Gastrointestinales/complicaciones , Humanos , Complicaciones Intraoperatorias/epidemiología , Masculino , Persona de Mediana Edad , Cuidados Paliativos , Falla de Prótesis/economía , Estudios Retrospectivos , Seguridad , Stents/efectos adversos , Esterilización , Tasa de Supervivencia , Resultado del Tratamiento
4.
Artículo en Inglés | IMSEAR | ID: sea-65779

RESUMEN

BACKGROUND: Precut papillotomy enhances the success of selective bile duct cannulation. Doubts have been raised about the relative safety of the procedure. This study was undertaken to assess the success rate and complications of precut papillotomy using a needle knife. METHODS: 100 consecutive patients undergoing precut papillotomy for biliary endoprosthesis placement were studied. A needle knife was used in these patients after bile duct cannulation was not successful using other techniques. The success rate, complications and mortality were determined. RESULTS: Selective bile duct cannulation was achieved in 65 patients. There were six complications: bleeding (3), pancreatitis (2), and perforation (1). One patient died following duodenal perforation. The success rate for endoprosthesis placement was increased by 14.2% following precut papillotomy. CONCLUSIONS: Precut papillotomy enhances the success of selective bile duct cannulation, with complication rates similar to standard papillotomy.


Asunto(s)
Ampolla Hepatopancreática/cirugía , Neoplasias de los Conductos Biliares/complicaciones , Colangiopancreatografia Retrógrada Endoscópica , Colestasis/etiología , Neoplasias de la Vesícula Biliar/complicaciones , Humanos , Esfinterotomía Endoscópica/efectos adversos , Stents , Instrumentos Quirúrgicos
5.
Indian J Cancer ; 1997 Mar; 34(1): 16-9
Artículo en Inglés | IMSEAR | ID: sea-50150

RESUMEN

A patient of familial adenomatous polyposis (FAP) without extra intestinal lesions is presented. The patient underwent a proctocolectomy with J pouch ileal reservoir with an ileoanal anastomosis. The clinical course was further complicated by an adenocarcinoma developing in the J pouch. This was excised totally and a terminal illeostomy was constructed. The aim of doing a prophylactic proctocolectomy in familial polyposis coli is to prevent a malignancy developing and to restore function with an illeoanal pouch. However polyps can occur in the gastric, duodenal and intestinal mucosa, which can lead to malignancy. Greater awareness and close follow up is needed even after prophylactic proctocolectomy.


Asunto(s)
Adenocarcinoma/etiología , Poliposis Adenomatosa del Colon/cirugía , Femenino , Humanos , Masculino , Proctocolectomía Restauradora/efectos adversos
6.
Artículo en Inglés | IMSEAR | ID: sea-65769

RESUMEN

Synchronous lymphoma and adenocarcinoma of the colon are extremely rare. A 32-year-old woman was referred to us for colon cancer. Investigations revealed two primary tumors, one in the cecum and the other in the sigmoid colon. Subtotal colectomy with ileorectal anastomosis was performed. Histology revealed the cecal tumor to be non-Hodgkin's lymphoma, diffuse small cell type with plasmacytoid features. The sigmoid colon tumor was moderately differentiated adenocarcinoma. The patient received 6 cycles of chemotherapy postoperatively for lymphoma but died of recurrent disease after 17 months.


Asunto(s)
Adenocarcinoma/complicaciones , Adulto , Neoplasias del Ciego/complicaciones , Terapia Combinada , Resultado Fatal , Femenino , Humanos , Linfoma no Hodgkin/complicaciones , Neoplasias Primarias Múltiples/patología , Neoplasias del Colon Sigmoide/complicaciones
8.
Artículo en Inglés | IMSEAR | ID: sea-63744

RESUMEN

Spontaneously occurring liver cell adenoma is an extremely rare event. One such tumour in an adult male which was resected surgically is reported here.


Asunto(s)
Adenoma de Células Hepáticas/diagnóstico , Humanos , Hígado/patología , Neoplasias Hepáticas/diagnóstico , Masculino , Persona de Mediana Edad
9.
Artículo en Inglés | IMSEAR | ID: sea-65695

RESUMEN

OBJECTIVE: To study the clinico-pathological features of patients with solid and cystic papillary neoplasm of the pancreas. METHODS: The clinico-pathological features of solid and cystic papillary neoplasm of the pancreas were studied in seven fully documented and confirmed cases presented during the last seven years. RESULTS: All the patients were women with a median age of 18 years (range 12-40). Four presented with epigastric pain and three had a painless abdominal lump. The median duration of symptoms prior to presentation was 3 months (range 1-6). The tumor size ranged from 6-16 cm (mean 10 cm). Preoperative diagnosis was established by fine needle aspiration cytology in three patients. All the seven underwent resection. Pericapsular adhesions were found in two patients. All the patients were free of disease on follow-up ranging from 3-60 months (median 16 mo). CONCLUSION: Occurrence in young females, solid and cystic areas on imaging, resectability in spite of large size, and good prognosis are the important features of this tumor.


Asunto(s)
Adolescente , Adulto , Factores de Edad , Carcinoma Papilar/patología , Niño , Femenino , Estudios de Seguimiento , Humanos , Neoplasias Pancreáticas/patología , Pronóstico
10.
Indian J Cancer ; 1993 Sep; 30(3): 146-50
Artículo en Inglés | IMSEAR | ID: sea-51166

RESUMEN

Four cases of gastric cancer presenting with bone pain due to metastasis as the initial symptom are reported. Investigations revealed solitary osteolytic metastasis in the mandible in one, and left scapula in one patient. Third patient had multiple osteosclerotic metastasis with elevation of acid phosphatase and another had multiple discrete osteolytic metastasis simulating multiple myeloma. All the primary gastric cancers were poorly differentiated adenocarcinoma and three were of Borrman type III on gross appearance. One patient had sparing of the liver inspite of extensive metastasis. Chemotherapy was in effective in two patients and the prognosis was uniformly poor.


Asunto(s)
Adulto , Anciano , Neoplasias Óseas/secundario , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Gástricas/patología
11.
Artículo en Inglés | IMSEAR | ID: sea-63590

RESUMEN

Intraoperative fine needle aspiration cytology (FNAC) for pancreatic and ampullary lesions was carried out under direct vision using transduodenal approach in 97 patients. Cytological findings were classified as follows: positive for malignancy, suspicious for malignancy, benign (normal) cells from duodenum or pancreas, inflammatory and non-representative smears. Suboptimal smears (non-representative, suspicious and inflammatory) were excluded for calculating decision analysis values. Sensitivity for malignancy was 90.5% and specificity 100%. Positive and negative predictive values were 100% and 50% respectively. We conclude that intraoperative FNAC is useful in diagnosing malignant lesions of the pancreas.


Asunto(s)
Biopsia con Aguja/métodos , Carcinoma/patología , Citodiagnóstico , Humanos , Periodo Intraoperatorio , Páncreas/patología , Neoplasias Pancreáticas/patología , Valor Predictivo de las Pruebas , Sensibilidad y Especificidad
12.
Artículo en Inglés | IMSEAR | ID: sea-63992

RESUMEN

BACKGROUND: Endoscopic laser therapy is widely used in the palliation of advanced malignant colorectal diseases. The role of this therapy in improving the quality of life of these patients needs adequate assessment. METHODS: Nine patients with advanced colorectal cancers and three patients with secondary colorectal involvement by pelvic cancers underwent endoscopic Nd:YAG laser therapy for palliation using non-contact laser guides for tumor bleeding alone (n = 12) or associated with obstruction (n = 7). The therapy was performed on an outpatient basis in 9 of the 12 patients. One patient was lost to follow up. RESULTS: Symptom control was achieved in all the 11 bleeding tumors and in 5 of the 7 obstructive tumors. There were no major complications. Three patients had no improvement in the quality of life in spite of control of symptoms. CONCLUSION: Ambulatory endoscopic laser therapy is a minimally invasive, safe and effective method of palliation for selected patients with non-resectable malignant colorectal tumors.


Asunto(s)
Adulto , Anciano , Atención Ambulatoria , Colonoscopía , Neoplasias Colorrectales/radioterapia , Femenino , Humanos , Terapia por Láser , Masculino , Persona de Mediana Edad , Cuidados Paliativos
13.
Artículo en Inglés | IMSEAR | ID: sea-64311

RESUMEN

To study radiation-induced pancreatic duct damage, endoscopic retrograde pancreatograms of 11 patients with primary gastric lymphoma who had completed chemotherapy and moderate dose external radiation therapy were compared with those of 22 normal subjects. No significant alteration was seen in the length and caliber of the main pancreatic duct and number of side branches. Clubbing of one or two side branches was observed in four patients who had received radiation (p = ns). We conclude that significant structural changes do not develop in the pancreas following moderate dose upper abdominal radiation.


Asunto(s)
Adulto , Colangiopancreatografia Retrógrada Endoscópica , Terapia Combinada , Femenino , Humanos , Linfoma/terapia , Masculino , Conductos Pancreáticos/efectos de la radiación , Estudios Prospectivos , Tolerancia a Radiación , Radioterapia/efectos adversos , Neoplasias Gástricas/terapia
14.
Artículo en Inglés | IMSEAR | ID: sea-65825

RESUMEN

Segment III cholangio-enteric anastomosis was performed in 17 patients with obstructive jaundice due to unresectable malignancies at the porta hepatis. The operative mortality was 6% (1/17) and morbidity 30% (5/17). More than 50% fall in bilirubin level with symptomatic improvement in pruritus was seen in 13 patients. Three patients had 25%-50% fall in bilirubin level. This procedure is safe and effective in palliation of unresectable hilar obstruction.


Asunto(s)
Adulto , Anciano , Anastomosis Quirúrgica , Neoplasias de los Conductos Biliares/cirugía , Conductos Biliares/cirugía , Colestasis Extrahepática/cirugía , Femenino , Humanos , Yeyuno/cirugía , Masculino , Persona de Mediana Edad , Cuidados Paliativos
15.
Artículo en Inglés | IMSEAR | ID: sea-65730

RESUMEN

Adenoma of the ampulla of Vater is one of the extracolonic manifestations of familial polyposis coli (FPC). We report three patients with FPC in whom villous adenoma of the ampulla was detected. An adenoma carcinoma sequence has been suggested in such lesions.


Asunto(s)
Adenoma/patología , Poliposis Adenomatosa del Colon/patología , Adulto , Ampolla Hepatopancreática , Neoplasias del Conducto Colédoco/patología , Humanos , Masculino , Persona de Mediana Edad , Neoplasias Primarias Múltiples/patología
18.
J Indian Med Assoc ; 1973 Aug; 61(3): 134-6
Artículo en Inglés | IMSEAR | ID: sea-103078
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