RESUMEN
The present study was carried out to determine the total carbohydrate dynamics in the non infected and infected muscle samples of Nemipterus japonicus, harboured with pathogenic Klebsiella pneumoniae and Vibrio vulnificus. About twenty seven fish collected from the coast off Visakhapatnam, identified with lesions were undergone microbial analysis to isolate the incriminating pathogenic bacteria. The total muscle carbohydrate levels were analysed by Dubois method. The estimated total carbohydrates in the infected fish were found significantly higher as compared to the non infected fish. Thus it can be concluded that an increase of carbohydrate concentrations in infected fish may cause harmful physiological effects, reducing the immune response of the fish to the microbial organisms.