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Objective To investigate the therapeutic effect of autologous transplantation of spleen on rat liver cancer induced by DEN. Methods Forty rats were randomly divided into A and B group on average. Total spleens of 40 rats were resected, which preserved in liquid nitrogen. All splenectomy rats were feeded with DEN to induce hepatocellular carcinoma. After 12 weeks ,all rats which had were successfully induced liver cancer were transplanted by autologous spleen in group A. Group B were sham operation as control. Results Survival period was significantly higher in group A than that in group B. But transplanted splenic tissue had not recovered to normal morphological structure until these rats died. Conclusion Autologous transplantation of spleen has therapeutic effect for liver cancer induced by DEN.
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Objective To explore the diagnosis effect of B-US、CT、MRI and ERCP for hepatolithiasis. Methods Clinical data of 529 patients with hepatolithiasis who were admitted to hospital from January 2000 to January 2015 were retrospectively analyzed. The susceptibili-ty differences in intrahepatic stone, hepatic lobe lesion, stenosis and cholangiectasis of bile duct were statistically analyzed through different imaging checks, namely B-US, CT, MRI , ERCP, B-US+CT, B-US+MRI and B-US+ERCP. Results B-US and MRI showed highest sensitivity for intrahepatic stone. CT and MRI showed highest sensitivity for hepatic lobe lesion. B-US and MRI showed the highest sensitivity for cholangiectasis of bile duct. ERCP and MRI showed highest sensitivity for bile duct stenosis. The combined application of B-US and MRI is comprehensive diagnosis for hepatolithiasis. Conclusion B-US associated with MRI is the best methods of imaging check befor hepatolithi-asis surgery.
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Objective To analyze whether there is statistic significance among sex,age and outcome of patients suffering from intrahepatic stones,who were grouped according to our clinical pathologic staging proposed recently by professor Dong Jia-hong.Methods Totally 1 259 cases of intrahepatic stones were included.Statistic difference of different typing in sex,age,therapeutic methods and outcome was analyzed by SPSS 11.0 software.Results All types and subtypes by our clinical pathologic stage for intrahepatic stones have statistic difference in therapeutic methods and outcome.Conclusion Our clinical pathologic staging is a reasonable typing method for intrahepatic stones.