Conservative Management Of Ameloblastoma In An Adolescent Patient

Introduction- Ameloblastoma is an aggressive, benign odontogenic tumour of the jaw with varying clinical features and histologic patterns. The treatment options of en block and segmental resection reduce the chance of recurrence. Resection of the mandible is associated with many complications like loss of jaw bone integrity, deformity, dysfunction, cosmetic and psychological distress. For these reasons, young, growing patients find these treatment options simply unacceptable. An alternative method for young growing patients is the conservative approach. Materials and methods- Enucleation and chemical cauterization of the lesion with carnoy's solution (6% ethanol, 3%chloroform, 1% acetic acid, 1 gm ferric chloride) followed by iodoform dressing routinely. Results- Patient was followed up for 1.5 year. No recurrence was noticed. Conclusion-In young growing patient a more conservative approach with close postoperative follow-up will significantly reduces the morbidity

Serum Lipid Profiles in Breast Carcinoma and Benign Breast Diseases in Rohilkhand Region of Uttar Pradesh.

Aim: The study was carried out with an aim to evaluate an association of serum lipid profile with breast carcinoma and benign breast disease. Methods: For this purpose, a case-control study was planned in which a total of 105 subjects were enrolled according to a purposive sampling design - A total of 35 (33.3%) patients in each group having breast carcinoma, benign breast disease, and healthy controls were included for assessment. Lipid levels were assessed. Data were analyzed. Results: Age of subjects enrolled in the study ranged from 16 to 58 years. The mean age of subjects in malignant, benign and control group was 45.71 ± 10.04, 24.91 ± 6.83 and 35.60 ± 12.42 years, respectively. The majority of malignant cases were in advanced stage (T3 and T4), together accounted for 94.29% of total malignant cases. The remaining 2 (5.7%) cases were in T2-stage. A total of 21 (60%) cases had metastasis too. Mean triglyceride (TG) levels of malignant cases were significantly higher as compared to that of benign and healthy controls. Mean serum high density lipoproteins levels were significantly higher in benign group as compared to healthy controls. Mean serum low density lipoproteins levels were maximum in healthy controls and minimum in benign breast disease group. Statistically, the difference between healthy controls and benign breast disease was also found to be significant. Conclusion: For different lipid components, the relationship with different types of breast lesions was found to be varying. In malignant cases, TG levels showed an increased trend. The possibility of these relationships being random cannot be ignored. A larger study on larger sample size is recommended.