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Objective: To observe the discussion colour to exceed to check the correlation of carotid atherosclerosis and cerebral infarction. Methods: Choose 144 cases of cerebral infarction patients as observation group;And there is no history of high blood pressure, to select 138 cases of cardiovascular disease and diabetes in old people as control group, the two groups do colour to exceed carotid check, observation analysis of the plaques and hemodynamic index. Results:the observation group of patients with carotid artery plaque detection rate was 76.4%;Peak systolic velocity(PSV), end-diastolic velocity(EDV), significantly lower than the control group, the difference was statistically significant (t=5.32, t=5.64, P<0.05);Vascular resistance index(RI), blood vessels, pulsation index (PI) is significantly higher than the control group, the difference was statistically significant(t=6.23, t=3.56, P<0.05). Conclusion:the incidence of cerebral infarction is associated with carotid atherosclerosis, unstable plaque is the main risk factors.
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Objective:To evaluate the ultrasound diagnostic value of extrahepatic bile duct diseases and misdiagnosis reasons for leakage.Methods: For the diagnosis of 399 cases of extrahepatic bile duct diseases were retrospectively analyzed, analysis of the ultrasonic diagnosis. Results: Three hundred and ninty-nine cases of extrahepatic bile duct disease, ultrasonic diagnosis diagnosis coincidence rate 93.2% (372/399). With extrahepatic bile duct stones coincidence rate 94.5%, extrahepatic bile duct carcinoma (89.3%, 86.0%, biliary ascariasis bile duct cystic expansion 100%, 27 cases of misdiagnosis.Conclusion: Ultrasound in the diagnosis of extrahepatic bile duct diseases with high value.
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Objective: To establish a method for the determination of cyasterone in Shenshixiao capsules. Methods: Using an HPLC method, the column was an Agilent C18 (250 mm × 4. 6 mm,5 μm) column, the mobile phase was methanol-water with gradient elution. The detection wavelength was 243nm, the flow rate was 1. 0 ml·min-1 ,and the temperature of column was room temperature. Results:The linear relationship of cyasterone was good within the concentration range of 0. 025-0. 247 μg(r=0. 999 6), the average recovery was 99. 4%, and RSD was 0. 76%. Conclusion:The method is rapid, simple and accurate, and can be used in the quality control of the preparation.
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BACKGROUND: Total isoflavones of pueraria (TIP) possesses estradiol-like structures and has inhibition effect on bone loss or osteopenia in ovariectomized rats. However, studies have demonstrated that the prevention and treatment effect of TIP on osteoporosis in ovariectomized rats is poor, especially in single utilization. OBJECTIVE: To investigate the combination effect of TIP and vitamin D on the treatment of osteoporosis in ovariectomized rats. METHODS: Totally 81 female sprague-drawly (SD) rats of 3-month-old were randomly assigned into 9 groups. Exception those in the sham-surgery group, all rats were prepared for ovariectomized models. Vitamin D or low-, middle- and high-dose TIP or low-, middle- and high-dose TIP combined with vitamin D were intragastric administrated in the vitamin D, TIP or combination groups, respectively. There was no drug medication in the model and sham-surgery groups. The uterus coefficient was calculated at 3 months after medication. The serum alkaline phosphatase (ALP) activity, calcium, phosphonium, bone gla protein, estradiol levels, as well as bone mineral density of femur was determined. RESULTS AND CONCLUSION: Compared with the model group, the uterus coefficient and estradiol level was obviously increased in the middle- and high-dose TIP groups and all combination groups (P < 0.05); the ALP and bone gla protein levels significant decreased (P < 0.05); and the bone mineral density of central and distal femur were notably increased (P < 0.05); in particular, the result was more manifest in the high-dose combination group. TIP and vitamin D presented with synergism in uterus coefficient, estradiol, ALP, bone gla protein levels and bone mineral density of distal femur, but the effect was not significant in the calcium and phosphonium levels in the TIP and/or vitamin D groups. The findings demonstrated that Tip combined with vitamin D can induce synergism on prevention and cure of osteporosis in ovariectomized rat.