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1.
Indian J Pathol Microbiol ; 2012 Jan-Mar 55(1): 28-32
Artículo en Inglés | IMSEAR | ID: sea-142171

RESUMEN

Context: The need to perform reporting of renal biopsies of antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitides in a more uniform manner required relook at our eight-year data. Aims: To document detailed renal histopathology of pauci-immune rapidly progressive glomerulonephritis (RPGN) and also to seek any significant differences in renal histology of C-ANCA-positive, P-ANCA-positive, and ANCA-negative patients. Materials and Methods: A detailed analysis of the histopathologic features of renal biopsies of 48 patients in whom a diagnosis of pauci-immune glomerulonephritis was concluded on renal biopsy and who presented clinically as rapidly progressive renal failure was done. Statistical Analysis Used: One-way ANOVA and Pearson Chi square tests. Results: Compared with ANCA +ve patients, the ANCA -ve patients were much younger (46.85 ± 16.12 years vs 34.28±15.94 years). No significant differences were found between renal lesions of C-ANCA, P-ANCA, and ANCA-negative patients, except for diffuse tubular atrophy which was more severe and more frequently present with P-ANCA positivity (P value=0.013). Conclusions: Pauci-immune RPGN (irrespective of ANCA status) is a relatively rare disorder in patients who are undergoing the renal biopsy at our institute, constituting 2% of all renal biopsies submitted. It is mandatory to have ANCA serology status during reporting of a kidney biopsy showing pauci-immune crescentic or necrotizing glomerulonephritis. Also, if a uniform reporting strategy is followed throughout the country, the studies from this vast country will be comparable.


Asunto(s)
Adolescente , Adulto , Anciano , Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/complicaciones , Vasculitis Asociada a Anticuerpos Citoplasmáticos Antineutrófilos/patología , Anticuerpos Anticitoplasma de Neutrófilos/sangre , Biopsia , Niño , Preescolar , Femenino , Glomerulonefritis/patología , Histocitoquímica , Humanos , Inmunohistoquímica , Lactante , Riñón/patología , Masculino , Microscopía , Persona de Mediana Edad , Estudios Retrospectivos
2.
Indian J Pathol Microbiol ; 2006 Apr; 49(2): 286-8
Artículo en Inglés | IMSEAR | ID: sea-73953

RESUMEN

Hypertrophic pachymeningitis (HP) is a rare chronic inflammatory process that causes thickening of the dura leading to compressive myelopathy. HP has diverse etiologies like infections, chronic inflammatory processes, collagen vascular diseases and malignancy. We report one such case of HP who presented with compressive myelopathy, underwent decompressive surgery and died due to complications of surgery with the original disease process.


Asunto(s)
Adulto , Diagnóstico Diferencial , Duramadre/patología , Resultado Fatal , Humanos , Hipertrofia , Masculino , Meningitis/diagnóstico , Sarcoidosis/diagnóstico , Compresión de la Médula Espinal/diagnóstico
3.
Indian J Pathol Microbiol ; 2005 Oct; 48(4): 472-4
Artículo en Inglés | IMSEAR | ID: sea-74141

RESUMEN

We report a fatal case of disseminated strongyloidiasis masquerading clinically as stage IV caecal malignancy diagnosed at post mortem by needle necropsy. The parasite was seen in the smears from CSF, pleural fluid, ascitic fluid, splenic aspirate, lung aspirate and aspirates from caecal area. Enteric organisms like Group D streptococci and candida sp were also associated. We believe that this is the first report of widespread dissemination of S. stercoralis in AIDS from India.


Asunto(s)
Infecciones Oportunistas Relacionadas con el SIDA/diagnóstico , Adulto , Animales , Neoplasias del Ciego/diagnóstico , Errores Diagnósticos , Resultado Fatal , Humanos , India , Masculino , Strongyloides stercoralis , Estrongiloidiasis/complicaciones
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