A Rare Case of Factor Xii Deficiency in a Pregnant Woman

@#Factor XII deficiency, also known as the Hageman factor, is a rare disorder that has not been associated with any adverse outcomes. It is an interesting blood disorder whereby in the state of deficiency, it causes prolongation activated partial thromboplastin time (aPTT) which is correctable with mixing test. Although there have been case reports that have mentioned events of thrombosis and bleeding, however, no clear causal relationship has been established. Evidence for adverse events occurring in patients with Factor XII deficiency is sparse. We report here a case of a lady with a history of miscarriages who was incidentally found to have Factor XII deficiency during a routine workup for prolonged aPTT.

Ochrobactrum anthropi Bacteremia with Variable Clinical Course: Report of Two Cases

@#Ochrobactrum anthropi is a rare nosocomial pathogen that is manifesting itself mostly in immunocompromised patients and those with indwelling catheters. Identification of the microorganism is challenging and the ability to survive in aquatic surroundings have made it a clinically significant pathogen. Furthermore, the clinical picture of O. anthropi infection, is not well described. It may manifest in any form of clinical infections though bacteremia is the most common mode of presentation reported in the limited literature. We report here two cases of O. anthropi bacteremia presenting in an immunocompetent and an immunocompromised host respectively with different clinical manifestation and response. In view of the highly variable presentation of O.anthropi, a high index of suspicion must be given to at risks patients to ensure the timely diagnosis and optimal clinical outcome.

Streptococcus plurianimalium Peritonitis in a Patient on Continuous Ambulatory Peritoneal Dialysis: A Case Report

@#Streptoccoccus plurianimalium is a rare pathogen that has recently made a crossover from its common host, animals to humans. As reports start to emerge from this pathogen, it has come to light that it can cause clinically significant infections in a broad spectrum of systems. However, the mode of transmission of this pathogen has not yet been fully established. We report here a case of Streptoccoccus plurianimalium peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis in our centre. To the best of our knowledge, this is the first case report of a Streptoccoccus plurianimalium peritonitis in an end-stage kidney disease patient.