​A Retrospective Comparison of Mortality in Hematological versus Non-Hematological Malignancies in Cancer Intensive

Objective: The objective of this study was to study the demographic data and clinical outcome of cancer patient admitted inintensive care unit (ICU).Materials and Methods: Data of cancer patients admitted in ICU of tertiary care hospital between August 2017 and September2018 were reviewed retrospectively.Results: During the study period, 441 cancer patients were admitted in ICU. Majority of patients were male (58.27%). The mostcommon reason for ICU referral was respiratory problem (31.75%) followed by cardiovascular (26%). Lung carcinoma wasthe most common among solid malignancy, whereas lymphoma was the most common hematological malignancy. Patientswith hematological malignancy were relatively younger (55 years vs. 63 years). Patients who required inotropes/vasopressorsor mechanical ventilation had poor prognosis than the others. The mortality rate was higher in patient with hematologicalmalignancy than solid malignancy patients.Conclusion: The demand for intensive care for critically ill cancer is increasing, and considering the improvement in prognosiscancer patients should not be denied ICU care merely on the basis of a patient suffering from cancer. Data suggest that admittingselected patient with cancer to ICU is justifiable, but mere admitting patents for end of life care is not recommended.

Smoking associated with malignancy, hypertension, chronic obstructive pulmonary disease and concurrent coronary artery disease: report of nine cases.

Tobacco smoking in any form is a major risk factor for coronary artery disease (CAD), hypertension (HTN), chronic obstructive pulmonary disease (COPD), oral, nasopharyngeal, bronchial and other visceral malignancies. Cessation of smoking exerts considerable beneficial effect on development, recurrence and prognosis of these diseases. Present communication is based on the study of nine cases who had concurrent CAD, HTN, COPD and mitotic and/or pre malignant lesions due to unabated smoking. The youngest patient was a 35-year-old male having a smoking index of 300, presenting with acute coronary syndrome, COPD, HTN and buccal leukoplakia. Associated genitourinary malignancies in two cases and osteosarcoma in one case was an unusual presentation. These cases highlight the prognosis and public health implications of continuous smoking.