RESUMEN
Transmissible venereal tumor is a common disease of dogs which has been diagnosed since eighteen century. Several methods have been suggested for the treatment of this disease but due to many reasons including the relapse of tumor especially by surgical intervention, expense of facilities and so on, chemotherapy using antineoplastic durgs has been preffered. The authors have treated 10 cases of such disease in german shepherd dogs using vincristic. Nearly all of the cases were the habitants of north west region of Tehran, and Karaj. The animals were treated weekly by intravenous rout in all the cases. The tumors regressed after the 5th injection, without any problem. There has been no relapse of tumor except one case which the owner didn't present the animal regularly; So the tumor relapsed and another course of chemotherapy again constituted, and finally the result was excellent. In General the outcome was excellent for all the cases