Effect of moderate and severe anemia on fetal cerebral hemodynamic

The purpose of this study was to evaluate the effect of moderate and severe anemia on fetal cerebral hemodynamic. prospective study. This study was carried out in Al-Hussein University Hospital, from May 2003 to May 2004. The study carried out on 30 pregnancies with moderate anemia [maternal hemoglobin level less than 10 gm/dl and more than 6 gm/dl] group I and 6 pregnancies with severe anemia [maternal hemoglobin level less than 6 gm/dl] group II. Group II only with severe anemia was admitted to Al-Hussein Hospital. All pregnant women and fetuses were investigated on the first visit, doppler ultrasound was carried out on umbilical and cerebral fetal blood vessels and re-evaluated after treatment. The cerebral and umbilical doppler indices, amniotic fluid index and biometry were lower in group II at first visit. After treatment, the cerebral index and the cerebral to umbilical resistance ratio increased only in group II. Severe anemia leads to fetal cerebral vasodilatation and reduced amniotic fluid volume

rationale for prostate cancer detection in a developing country: comparison of screening and case finding

Objective: This study was conducted to compare the results of community based screening program for prostate cancer with case finding among urologic patients. Patients and Methods: Two programs for prostate cancer detection were conducted based on PSA assay [cutoff value 4ng/ml] and DRE for men aged 50 to 75 years. The first one included 833 urologic patients [group 1] and the second included 882 men who responded to a campaign for early detection of prostatic diseases [group 2]. Diagnosis of prostatic adenocarcinoma depends on ultrasound guided six-core prostatic biopsies. Results: In group 1, 154 patients were biopsied [147 due to high PSA +/- suspicious DRE and 7 due to suspicious DRE alone]. Prostate cancer was diagnosed in 36 patients [4.3%]. Organ confined cancer was detected in 41.7% of them [15 patients]. In group 2, 75 men were biopsied [69 for high PSA +/- suspicious DRE and 6 for suspicious DRE alone].The cancer detection rate was 2.2% [19 patients] and the rate of organ confined disease was 37.87 [7 patients]. There was no significant statistical difference between both groups regarding cancer detection rates and the percent of organ confined tumors. Conclusion: The results of this study may present a rationale for application of prostate cancer detection program in developing countries to urologic patients