Clinical aspects, laboratory manifestation and serologic studies of a newly observed arbor a virus infection

18 cases of Chikungunya (or a very closely related virus) infection, a newly observed clinical entity in the Philippines, are presented. Diagnosis was established by serological studies consisting of hemagglutination-inhibition (HI) and complement fixation (CF) tests. (Summary)

Viruses of the respiratory tract in Filipinos I. Para influenza types 1 and 3

In 279 serums of young adults with ages ranging from 12 to 24 tested by HI against para influenza types 3 and 1 viruses, incidence rates of 76% and 25% were obtained respectively after 20% had been deducted from each of the rates due to heterotypic responses. This is very suggestive of a widespread infection due to para influenza 3 in the Philippines. (Summary)

Virological studies of hospitalized cases of poliomyelitis

One hundred nine cases of poliomyelitis admitted to the Polio Pavilion of the San Lazaro Hospital in 1961 were studied. At least paired serum samples and in some instances, triple serum samples were collected from them. Ninety-one had matching stool specimensVirus isolation was done on the 91 stool samples and complement fixation test on the 129 paired or triple serum samplesThe pertinent findings were as follows: (1) only half of the cases clinically recognized as poliomyelitis could be confirmed by either or both tests employed; (2) about one-third of the agents isolated from stools were non-polio; (3) the most prevalent type of poliovirus causing clinically apparent illness is type 1. The least common is type 2; (4) poliomyelitis is still an infantile type of disease in this country since the majority of the confirmed cases occurred in the age group 0-23 months; (5) maternal antibodies may cease to be protective even before an infant reaches 4 months of age; (6) during the period of study, cases of poliomyelitis were more or less evenly distributed throughout the year. (Summary)

Bacterial and sensitivity study of local cases of chronic suppurative otitis media

Chronic exudative otitis media usually results in impaired hearing and/or grave complications. Various predisposing factors, such as congenital or acquired anatomical barriers to drainage, allergy, systemic disease and low resistance of the patient, play a big role in its production. The exciting factor is usually bacterial in origin. This paper is chiefly concerned with the determination of the kind of organisms and their sensitivity reactions to various drugs, that may be encountered in cases of chronic exudative otitis media. For this purpose, cultures were made of material taken from the middle ear of patients with chronic otitis media. (Author)