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Indian J Exp Biol ; 2007 Oct; 45(10): 901-6
Artículo en Inglés | IMSEAR | ID: sea-62119

RESUMEN

Application of juvenile hormone esterase inhibitor 3-octylthio-1,1,1- trifluropropan-2-one (OTFP) to 5th instar nymphs and virgin females of D. cingulatus revealed the profound role played by juvenile hormone esterase (JHE) in metamorphosis and reproduction. The ability of OTFP to cause delay and the formation of malformed nymphs, suggests that inhibition of JHE in vivo maintains a higher than normal hemolymph JH titer. It is obvious that OTFP does inhibit in vivo JHE activity in late instar nymphs. Further, the application of JHE inhibitor, OTFP to virgin females demonstrates that substituted trifluropropanones can indirectly stimulate egg development by inhibiting JHE activity in virgin females.


Asunto(s)
Acetona/análogos & derivados , Animales , Hidrolasas de Éster Carboxílico/antagonistas & inhibidores , Cromatografía en Capa Delgada , Inhibidores Enzimáticos/farmacología , Insectos/efectos de los fármacos , Hormonas Juveniles/metabolismo , Ninfa/efectos de los fármacos
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