Detection of serum prostate specific antigen in lactating, pregnant, and advanced breast cancer Sudanese women

Although prostate-specific antigen [PSA] is the most valuable tumor marker for the diagnosis and management of prostate carcinoma, it is widely accepted that PSA is not prostate specific. The aim of this study is to address the possibility of using the PSA as marker for the sex assignment in different categories and relevance of this test in women problems. We have evaluated the measurement of serum total PSA for differentiation between Sudanese women with advanced breast cancer [n= 10], and those lactating [n=10], pregnant [n= 10] compared with 20 healthy women as control group. Serum total PSA [TPSA] was measured using immuno-radiometric assay [IRMA]. In this study the mean age was significantly higher in advanced breast cancer groups compared with lactating group [P<0.01]. The mean serum PSA levels in the healthy control women examined [n=20] was 0.72 +/- 0.55 vs. 1.18 +/- 0.92, 1.42 +/- 2.43 and 0.51 +/- 0.13 ng/ml in serum from advanced breast cancer [n=10], pregnant [n=10] and lactating women [n=10] respectively. A significant high level of total PSA in serum of advanced breast cancer compared with the normal group [P< 0.05]. These results indicated the possible use of total PSA to distinguish between healthy women and/or women with advanced breast cancer

Urological injuries during pelvic surgery in women, Gezira, central Sudan

Injuries to the ureter and bladder are common in female pelvic surgery, sometimes extremely common to be considered as traditional, This is a retrospective study conducted in Gezira Hospital for Renal Disease and Surgery, Medani Teaching Hospital and Medani Maternity Hospital, Wad Medani, Sudan. We included 82 patient's with urological injuries following obstetrical gynecology intervention in the previous 5 years. The interaoperative injuries constituted 20/82[24%], while the remote injuries were 62/82 [75.6%]. We conclude that the urological injuries are common complications during pelvic surgery, associated mainly with abdominal hysterectomies and Cesarean section