RESUMEN
Allergic rhinitis [AR] related inflammation might worsen the severity of obstructive sleep apnea [OSA], however, the relationship between the two disorders remains controversial. Our aim was to determine the prevalence of AR and atopic markers in OSA. This cross-sectional study recruited participants with sleeprelated complaints referred to a sleep center from February 2013 to June 2014. The diagnosis of OSA was based on the Berlin questionnaire [BQ] followed by confirmatory polysomnography [PSG]. The diagnosis of AR was made via focused history and clinical examination and was confirmed by measuring atopic markers. OSA was diagnosed in 97 out of 157 adults attending the sleep clinic [61.8%]. There was a high prevalence of AR [52.6%] among OSA individuals. This was not significantly different from the frequency in the non-OSA individuals [p = 0.5]. Elevated total immunoglobulin E [IgE; >100 K/micro L], eosinophil count, and positive Phadiatop tests were found in individuals with OSA to be 37.1%, 11.3%, and 41.2%, respectively. Individuals without OSA have shown similar percentages. In our cohort, there was no significant difference in frequency of AR and atopy among participants with OSA compared to those without OSA
Asunto(s)
Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Apnea Obstructiva del Sueño , Biomarcadores , Comorbilidad , Encuestas y Cuestionarios , Estudios Transversales , Arabia SauditaRESUMEN
To investigate the association between some demographic factors and the levels of severity among asthmatic children. Method: One hundred and twenty five asthmatic children aged between 6 months and 15 years were studied in pediatric and asthma clinics at King Abdul Aziz University Hospital [KAUH]. The assessment of clinical severity has based on the global strategy guidelines for asthma assessment and management. Subjects were grouped by age: infants [= 1 year], toddlers [1 - 3 years], preschool or kindergarten [3 - 6 years], school [6 - 12 years], and adolescents [12 - 15 years]. Demographic data [age and sex] here analyzed for any statistical significance. Boys were 80 [64%] and predominated in all age groups except in infants. 10 [8%] were infants 22 [17.6%] toddlers, 26 [20.8%] preschool or kindergarten. 49 [39.2%] school, and 18 [14.4%] adolescent, The levels of severity of asthma were intermittent 11 [8.8%,], mild persistent 74 [59.2%], moderate persistent 33 [26.4%], and severe persistent 7 [5.6%]. Frequency and severity of asthma were significantly higher in boys than girls [P < 0.05] and at school age compared to other age groups [P < 0.05]. Conclusion and recommendation: This study demonstrated an increase in the frequency and severity of bronchial asthma in boys, particularly, those at school age. As stated in the literature, correlating demographic factors and clinical status can help in the prediction of the severity of asthma and possibly its outcome. This demands greater vigilance in the care of this group of asthmatics more than any others