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Objective: To study caffeine and/or placebo implication as countermeasures during sleep deprivation (SD). Methods: A double-blind, within-subjects and counterbalanced design was employed and five trials were conducted. Subjects were exposed to 30h SD in each trial. No medicine was administrated in control trial while placebo 200mg, caffeine 200mg, caffeine 400mg and the combination of caffeine (200mg) and placebo (200mg) were administered, respectively in the other trials. Letter Cancellation Test was used to assess the alertness. Result: The correct concealing numbers per minute (CCNM) of the combination of caffeine and placebo (62.36?7.31/min), caffeine 400mg(55.88?6.54/min) and caffeine 200mg (59.48?6.52/min) were more than that of control(46.80?5.35 /min), P0.05). Conclusion: Caffeine and the combination of caffeine and placebo expectation can increase alertness.
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Objective:To study the effect of 30-min nap at three low points of the rhythm during 40-hour sleep deprivation Method:Eight young subjects having normal sleep-wake habits were subjected to nap and total sleep deprivation conditions at an interval of 2 weeks The whole experiment was from 6:00 of the first day to 22:00 totally 40 hours The typing workload was given There were three times of naps, which lasted 30 min every time, at 13:00 (the first day), 1:00 and 13:00 (the second day) Visual event related potentials were measured at 1:00 and the end Symbol recognizing task was given before the experiment, after each nap, at the end of it, and two days after Results:In the symbols recognizing task, whether sleep deprivation with or without naps, the reactive time prolonged, the number of right decreased, the number of lose increased Compared with total sleep deprivation, the reactive time was shortened apparently while the number of right and lose did not change when naps were introduced Whether sleep deprivation with or without naps, the latency of P300 was prolonged, the number of right decreased while the amplitude did not change Compared with total sleep deprivation, the latency was shortened apparently while the number of right and amplitude did not change when having naps Conclusion:Nap has positive effects during sleep deprivation
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Objective: To study the effect of 30-min nap at three low points of the rhythm during 40-hours sleep deprivation on continuous adding. Methods: Eight young subjects with normal sleep-wake habits were subjected to nap and total sleep deprivation conditions at an interval of 2 weeks. The whole experiment was from 6:00 of the first day to 22:00 of the second day, totally 40 hours. There were three times of nap which lasted 30 min every time, 13:00(the first day), 1:00 and 13:00(the second day). Continuous adding was given separately at the time before experiment,13:00 and 18:00 of the first day, 1:00,6:00,13:00,18:00 and 22:00 of the second day.and 2 days after the experiment;reaction times and wrong numbers were recorded. Results: Whether sleep deprivation with or without naps, the reaction time was prolonged.Compared with total sleep deprivation, the reaction time was shortened significantly at SD24, SD31 and SD40 when naps were introduced. Whether sleep deprivation with or without naps, the number of wrong answers did not change. Conclusion:Nap has positive effects during sleep deprivation.
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Objective: To explore the effects of ginsenosides(GS) on learning,memory and activity of rats during sleep deprivation(SD).Methods: SD was induced in Sprague-Dawlay rats by employing "flower pot" technique.The rats were randomly divided into five groups according to the time of SD(0-96h),and every group was also divided into two subgroups: experimental group(E) and control group(C).Forced feeding of GS to the experimental rats for 5 d before the rats were deprived of sleep.Before and after SD immediately,the behaviors of rats were studied in "Y" maze test,step-down test and open-field test.Results: ①"Y" maze test: As compared with those of the controls,the accuracy of response of experimental groups increased significantly in 24h,48h,72h and 96h(P
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Objective:To investigate the expression of c-Fos protein after total and partial sleep deprivation(SD) of 96 hours.Methods:SD was induced in the male Sprague-Dawley rats by housing them on the small platforms over water.Controls were housed in the normal cage(CC) or on the large platforms over water(TC).The effects of total and partial 96h SD on the expression of c-Fos protein were examined by immunocytochemisty.Results:SD made Fos protein express differently in the different fields of the brain.The expression of Fos protein of partial SD was wider and lighter than of total SD.Conclusion:Compared with total SD,partial SD has lighter stress.
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Objective:To confirm the least practice times to eliminate the practice effect in the Working Memory Test Method: Four volunteers from college students practiced the Working Memory Test many times in two consecutive days Their scores were analyzed Result:Comparing their results before and after practice, there were significant practice effects with two types, three levels In order to eliminate these effects, the practice times before formal test was no less than 18 Conclusion:Practice effect is one of the factors affecting the results of the Working Memory Test, which can be eliminate after at least 18 times practice
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A revolving drum, about 40cm in diameter, with vertical stripes on its surface, was used in examination. The drum was held 50cm in front of the eyes of aircrew receiving examination. The horizontal optokinetic nystagmus was elicited by vertical black stripes moving horizontally. The examinee was instructed to gaze straight ahead at the black stripes, without deliberate fixation. The drum speed was kept constant at 20?, 40?,60?,80?,100?,120?/s. The velocity of the slow component of nystagmus, its frequency, amplitude and symmetry were recorded when the reaction reached its peak.The slow component velocity and the frequency were increased with the drum speed, but the amplitude was decreased with the drum speed. The wave forms of optokinetic nystagmus were usually of five types.