Blind Eye Associated with Osteosarcoma.

We report the case of a 10 year old girl with a late diagnosis of a high grade osteosarcoma (Stage IIb) of the right femur in a low income setting. The diagnosis could clinically have been made much earlier if the observation of an enucleated congenitally blind left eye due to a probable retinoblastoma was known to be associated with osteosarcoma. Screening of at-risk families and close surveillance of affected individuals for these heritable genetic predisposition syndromes may permit earlier diagnosis and more effective treatment of osteosarcoma in these populations.

Burkitt's lymphoma in Cameroon: a review of 300 cases in two referral health facilities in Yaounde

In this descriptive retrospective study; we reviewed 300 cases of Burkitt's lymphoma (BL) diagnosed within 10 years from January 1; 2000 to December 31; 2010. The study took place in the pathology laboratories of the Central Hospital and the General Hospital in Yaounde; Cameroon. The aim was to review the anatomo-clinical and epidemiological aspects of the disease; especially with respect to its localization. We found that BL affected mostly children aged 5-14 years with peaks at 4 and 12 years. A slight male predominance was observed. The abdomino-pelvic site was more frequent (57.7%). Diagnosis of the tumor was mainly by fine-needle aspiration cytology (FNAC). About 6% of our patients tested positive for the human immunodeficiency virus (HIV). We recommend further in-depth studies to find out if there are any emerging factors that influence the localization of the disease in endemic areas or if our finding is incidental

Epidémiologie clinique du cancer du sein chez les moins de 40 ans

Le cancer du sein du sujet age de moins de 40 ans represente un probleme rare. Nous avons realise une analyse retrospective sur 133 patients qui nous a permis de montrer la place de ce cancer dans cette tranche d'ages. Nous avons ainsi recense 34;5de cas par rapport a l'ensemble des cancers du sein a l'hopital de Yaounde. Un antecedent familial de cancer et la multiparite ont ete les facteurs de risque les plus retrouves; respectivement 11 et 9 sur 32. Au moment du diagnostic la majorite des malades etaient au stade metastatique. Ce travail considere preliminaire nous a permis d'avoir une idee sur le profil de la camerounaise jeune atteinte du cancer du sein