Situation of domestic violence and health outcomes among married migrant women at reproductive age / 中华流行病学杂志

Objective To examine the association between domestic violence and mental/general health status among married migrant women at reproductive age. Methods A total of 958 eligible married migrant women of reproductive age who were selected through community-based multiple-stage sampling method in one urban district in Shanghai and interviewed in April and May 2010. Chi-square test,Fisher’s exact test and unconditional logistic regression model were used for data analysis. Results The overall prevalence of domestic violence in husbands was 40.0%. Among 5 adverse outcomes related to general health and 6 adverse outcomes related to mental health, exposing to physical or sexual violence in the life time or in the previous year were associated with 2 adverse outcomes related to general health(including often in pain/discomfort and sleeping problems) and 4 adverse outcomes related to mental health(including often feeling nervous/tense/worry,easily getting frightened,crying more than usual,often feeling worthless on herself or being indifferent to the surroundings). Experience of control behavior was associated with 1 adverse outcome that related to general health (often in pain or discomfort) and 3 adverse outcomes related to mental health including easily get frightened,feeling worthless on herself or indifferent to the surroundings, Experience of emotional violence in the previous year was associated with pain or discomfort feelings. Compared with those who had never experienced any violence from husband after adjusting for potential influencing factors in logistic regression models,respondents who had ever experienced physical or sexual violence,control behavior or emotional violence,the numbers were respectively, presented 2.25-3.70 times,1.94-4.75 times and 2.12 times,more likely to report the above-mentioned adverse health outcomes. Conclusion Domestic violence was associated with general and mental health among married migrant women at reproductive age,especially physical or sexual violence and control behaviors.

Situation of domestic violence and health outcomes among married migrant women at reproductive age / 中华流行病学杂志

Objective To examine the association between domestic violence and mental/general health status among married migrant women at reproductive age. Methods A total of 958 eligible married migrant women of reproductive age who were selected through community-based multiple-stage sampling method in one urban district in Shanghai and interviewed in April and May 2010. Chi-square test,Fisher’s exact test and unconditional logistic regression model were used for data analysis. Results The overall prevalence of domestic violence in husbands was 40.0%. Among 5 adverse outcomes related to general health and 6 adverse outcomes related to mental health, exposing to physical or sexual violence in the life time or in the previous year were associated with 2 adverse outcomes related to general health(including often in pain/discomfort and sleeping problems) and 4 adverse outcomes related to mental health(including often feeling nervous/tense/worry,easily getting frightened,crying more than usual,often feeling worthless on herself or being indifferent to the surroundings). Experience of control behavior was associated with 1 adverse outcome that related to general health (often in pain or discomfort) and 3 adverse outcomes related to mental health including easily get frightened,feeling worthless on herself or indifferent to the surroundings, Experience of emotional violence in the previous year was associated with pain or discomfort feelings. Compared with those who had never experienced any violence from husband after adjusting for potential influencing factors in logistic regression models,respondents who had ever experienced physical or sexual violence,control behavior or emotional violence,the numbers were respectively, presented 2.25-3.70 times,1.94-4.75 times and 2.12 times,more likely to report the above-mentioned adverse health outcomes. Conclusion Domestic violence was associated with general and mental health among married migrant women at reproductive age,especially physical or sexual violence and control behaviors.

Situation of domestic violence and health outcomes among married migrant women at reproductive age / 中华流行病学杂志

<p><b>OBJECTIVE</b>To examine the association between domestic violence and mental/general health status among married migrant women at reproductive age.</p><p><b>METHODS</b>A total of 958 eligible married migrant women of reproductive age who were selected through community-based multiple-stage sampling method in one urban district in Shanghai and interviewed in April and May 2010. Chi-square test, Fisher's exact test and unconditional logistic regression model were used for data analysis.</p><p><b>RESULTS</b>The overall prevalence of domestic violence in husbands was 40.0%. Among 5 adverse outcomes related to general health and 6 adverse outcomes related to mental health, exposing to physical or sexual violence in the life time or in the previous year were associated with 2 adverse outcomes related to general health (including often in pain/discomfort and sleeping problems) and 4 adverse outcomes related to mental health (including often feeling nervous/tense/worry, easily getting frightened, crying more than usual, often feeling worthless on herself or being indifferent to the surroundings). Experience of control behavior was associated with 1 adverse outcome that related to general health (often in pain or discomfort) and 3 adverse outcomes related to mental health including easily get frightened, feeling worthless on herself or indifferent to the surroundings, Experience of emotional violence in the previous year was associated with pain or discomfort feelings. Compared with those who had never experienced any violence from husband after adjusting for potential influencing factors in logistic regression models, respondents who had ever experienced physical or sexual violence, control behavior or emotional violence, the numbers were respectively, presented 2.25-3.70 times, 1.94-4.75 times and 2.12 times, more likely to report the above-mentioned adverse health outcomes.</p><p><b>CONCLUSION</b>Domestic violence was associated with general and mental health among married migrant women at reproductive age, especially physical or sexual violence and control behaviors.</p>

Do biochemical markers and Apa I polymorphism in IGF-II gene play a role in the association of birth weight and later BMI?

The aim of the study was to explore the mechanisms underlying the association of birth weight with later body mass index [BMI] from the biochemical markers related to metabolism and the Apa I polymorphism in IGF-II gene. A total of 300 children were selected randomly from the Macrosomia Birth Cohort in Wuxi, China. The height and weight were measured and blood samples were collected. Plasma concentrations of 8 biochemical markers were detected. Apa I polymorphism was analyzed by polymerase chain reaction-restriction fragment length polymer-phism [PCR-RFLP]. Biochemical markers were detected for 296 subjects and 271 subjects were genotyped for the Apa I polymorphism. No association was found between birth weight and 8 biochemical markers. In boys, the BMIs of AA, AG and GG genotypes were 16.10 +/- 2.24 kg/m[2], 17.40 +/- 3.20 kg/m[2], 17.65 +/- 2.66 kg/m[2]. And there was statistical difference among the three genotypes. But in girls, there was no statistical difference. The birth weights of AA, AG and GG genotypes were 3751.13 +/- 492.43 g, 3734.00 +/- 456.88 g, 3782.00 +/- 461.78 g. And there was no statistical difference among the three genotypes. Biochemical markers are not associated with birth weight. Apa I polymorphism may be related to childhood BMI, but it may be not associated with birth weight. Therefore, biochemical markers and Apa I polymorphism might not play a role in the association of birth weight and BMI

effect of high birth weight on overweight and obesity in childhood and adolescence. A cohort study in China

To determine the association of high birth weight [HBW] with the risk of obesity in childhood and adolescence. We also aimed to explore the interactions of HBW with physical activity and dietary habits. In a birth cohort born in 1993, 1994, and 1995 in Wuxi, China, subjects with a birth weight [BW] of >/= 4000 g were selected as the exposed group. For each exposed subject, one non-exposed subject with a BW of 2500-3999 g, matched by year of birth, gender, and type of institute at birth was chosen. Two follow-ups were performed from October 2005 to February 2007 and July 2010 to December 2011. A total of 1108 exposed and 1128 non-exposed subjects were included. Overweight/obesity rates were significantly higher in the exposed group [16.2% in childhood and 14.2% in adolescence] than those in the non-exposed group [12.1% in childhood and 8.2% in adolescence]. There was no significant interaction between BW and the growth period [F=2.10, p=0.147]. The relative excess risk due to interaction [RERI] of HBW with physical activity was -0.20 [95% CI=-2.85-2.45], and the RERI of HBW with dietary habits was 1.19 [95% CI=0.14-2.23]. Infants with HBW are at increased risk of childhood and adolescent overweight/obesity, and this relationship is not influenced by the growth period. There is an additive interaction between HBW and dietary habits

Effects of Bisphenol A on Male Reproductive Function / 环境与健康杂志

Recently,to assess the reproductive effects of bisphenol A (BPA),the environmental estrogen,has become a focus of stusy. Investigations,to date,have focused on the effects on the reproductive system including the morphogenesis of tissues and organs,endocrine and the toxic mechanisms of action,particularly in males. Based on the study results concerning BPA’s impacts on male reproduction,the further study directions in this field were presented in this paper.

Evaluación periódica del riesgo biopsicosocial prenatal en la predicción de las complicaciones maternas y perinatales en Asia 2002-2003 / Periodical assessment of the prenatal biopsychosocial risk to predict obstetric and perinatal complications in Asian countries 2002-2003

Objetivo: Describir el nivel de predicción de las complicaciones obstétricas y perinatales mediante la evaluación periódica del riesgo biopsicosocial prenatal (RBP) durante el control prenatal en mujeres asiáticas. Materiales y métodos: Durante el 2002 se evaluaron en Shanghai, China y Dhaka, Bangalesh 565 primigrávidas sanas con evaluaciones periódicas del RBP (primera: semana 14-27, segunda: semana 28-32, tercera: semana 33-42) con evaluación prospectiva del resultado materno y perinatal. Resultados: La edad promedio fue 25.1±6.4 años en su mayoría de nivel socioeconómico medio, con formación universitaria y residencia urbana. Se observaron 135 (23.9%) complicaciones obstétricas, 57 (10.1%) recién nacidos con bajo peso y 41 (7.3%) muertes perinatales. El alto riesgo biopsicosocial prenatal se asoció con las complicaciones obstétricas (área bajo la curva ROC) 0.80 IC 95% 0.71-0.89 con el parto prematuro (área bajo la curva ROC) 0.79, IC 95% 0.68-0.90) y con el bajo peso al nacer (área bajo la curva ROC) 0.85, IC 95% 0.77-0.93. El período con mayor efectividad predictiva fue el último (33-42 semanas) tanto para las complicaciones obstétricas (sensibilidad: 84.4%, especificidad: 69.3%), como para el parto prematuro (sensibilidad: 79.2%, especificidad: 67.1%) como para el bajo peso al nacer (sensibilidad: 88% especificidad: 77.3%). A pesar de las diferencias basales sociodemográficas, nutricionales, étnicas, culturales y religiosas de los dos países el efecto predictivo del instrumento fue similar. Conclusión: La evaluación del riesgo biopsicosocial prenatal fue clínicamente válida para predecir complicaciones obstétricas, parto prematuro y bajo peso al nacer en los países asiáticos comparable a los resultados en Latino-América.

Objective: To determine the effect of the periodical use of the prenatal biopsychosocial risk assessment (PBR) to predict obstetric and perinatal complications in pregnant women in Asian countries. Materials and methods: In Shanghai, China, and Dhaka, Bangladesh, 565 healthy primigravids were evaluated with PBR at inclusion (14-27 weeks), in a second time (28-32 weeks) and in a third time (33-42 weeks) with assessment of the perinatal outcome. Results: The average age was 25.1±6.4 years old. Most of the women were from middle socioeconomic level, with university academic degree and urban residence. There were 129 (25.6%) obstetric complications, 54 (10.1%) low birth weight babies and 41 (7.3%) perinatal deaths. The ROC analysis showed that the high PBR score was associated with obstetric complications (area under ROC Curves) 0.80 CI 95% 0.71-0.89, preterm birth (area under ROC curves) 0.79, CI 95% 0.68-0.90, low birth weight (area under ROC curves) 0.85, CI 95% 0.77-0.93. The best predictive period was the last (33-42 weeks) to obstetric complications (sensibility: 84.4%, specificity: 69.3%), preterm delivery (sensibility 79.2%, specificity 67.1%) and to low birth weight (sensibility 88%, specificity 77.3%). The baseline sociodemographic and nutritional characteristics and the perinatal outcome were different between the countries, however, the predictive effect of the instrument was similar. Conclusion: The prenatal biopsychosocial risk assessment was clinically valid to predict obstetric complications, preterm birth and low birth weight in two Asian countries when compared to results in Latin-American countries.

Efectos de la suplementacion oral con calcio y ácido linoleico conjugado en primigrávidas de alto riesgo / Effects of calcium and linoleic acid conjugated diet in pregnancy of high risk

Objetivo: Determinar el efecto de dosis bajas de calcio elemental y ácido linoleico conjugado sobre los niveles plasmáticos de tromboxano B2, insulina, aldosterona, GMP cíclico, proteína C reactiva ultrasensible y la eficacia del tratamiento en la prevención de la hipertensión arterial inducida por el embarazo. Métodos: En un ensayo clínico doble ciego, controlado con placebo se estudiaron a 48 primigrávidas con alto riesgo para desarrollar preeclampsia con dosis diarias de calcio elemental (600 mg) y ácido linoleico conjugado (450 mg) (n=24) ó 450 mg de talco y 600 mg de lactosa como placebo (n=24) desde la semana 18-22 hasta el parto. Resultados: Dos mujeres en el grupo experimental (8.3/100) desarrollaron hipertensión arterial inducida por el embarazo comparado con 10 (41.7/100) mujeres controles (riesgo relativo 0.20, IC 95/100 0.05-0.82, p=0.01). No se observaron diferencias entre los niveles plasmáticos después de 4 semanas de tratamiento ni efectos maternos o neonatales en ambos grupos. Conclusiones: La administración de dosis bajas de calcio elemental y ácido linoleico conjugado redujo significativamente la incidencia de hipertensión arterial inducida por el embarazo en mujeres embarazadas de alto riesgo sin efectos colaterales atribuibles a la intervención y sin efecto sobre los niveles de tromboxano B2, insulina, aldosterona, GMP cíclico y la respuesta sistémica inflamatoria