A Histopathologic Study of Pilosebaceous Changes in Psoriatic Lesion of the Scalp / 대한피부과학회지

BACKGROUND: Although there have been many studies on psoriasis, only a few studies have been conducted on pilosebaceous changes and even those results are controversial. While a few studies have been conducted on the morphological changes of the pilosebaceous unit in scalp psoriasis, comparative studies on the morphometric changes of pilosebaceous structures with a normal control group have not been conducted. OBJECTIVE: The purpose of this study is to elucidate the morphological change of the pilosebaecous unit in scalp psoriasis. METHODS: We conducted a comparative study an the morphometric changes of the pilosebaceous structure in 10 cases of scalp psoriasis with a normal control group. Results : The results of this study are summarized as follows : 1. Total hair counts, telogen hair counts, telogen hair counts, and the sizes of hairs and follicles in the lesional scalp showed no statistically significant increase than in the normal control. 2. The intrafollicular hyperkeratosis in infundibulum and sebaceous atrophy were more proininet in the lesional area than in the normal control area. These findings were also significantly prominent in the uninvolved normal-appearing area than in the normal control area. 3. Perifollicular inflammation, squamous metaplasia of the sebaceous gland and telangiectasia in the lesional and uninvolved areas were prominent, and these findings were not found in the normal control areas. Conclusion : The sebaceous atrophy and squamous metaplasia are very important findings of morphologic changes in psoriasis, and this paradoxical change may be an important clue to clarify the pathogenesis of psoriasis.

A Case of Plane Xanthoma Associated with Type IV Hyperlipoproteinemia

A case of plane xanthoma arising in type IV hyperlipoproteinemia in a 53-year old woman is reported. The patient had well-defined yellowish to orange colored slightly elevated plaques on both upper eyelids, cheeks, neck, and upper chest. The laboratory findings showed increased serum triglyceride on lipid profile, and widening of pre-beta band on electrophoresis lipoprotein. She had a fatty liver, mild hepatomegaly, but other systemic diseases such as multiple myeloma, leukemia and lymphoma were not found.

A Case of Benign Cytophagic Histiocytic Panniculitis / 대한피부과학회지

Cytophagic histiocytic panniculitis is a histiocytic disorder which is characterized by recurrent subcutaneous nodules, fever, pancytopenia, and abnormal hepatocyte function. Most patients had systemic involvement with hepatosplenomegaly and pancytopenia and, after a chronic course, usually developed a hemorrhagic diathesis that led to death. Rarely reported cases were shown to have had a non-fatal course. We report herein a case of cytophagic histiocytic panniculitis in the trunk and both upper arms of 34-year-old woman who had a benign course and also showed histopatholoigcally lipomembranous change in the subcutaneous lesion.

A Case of Primary Cutaneous Plasmacytoma , Observed for 10 years / 대한피부과학회지

A 28-year-old female devei,oped five rice-sized erythematous telaniectatic solid papules of her left side of cheek and numerous light brownish flat papules of her face two years before visiting our department of dermatology. Biopsy results of the erythematous papule vere dermal infiltration by well-differentiated, however, somewhat atypical and varying sized plasma cells involving epidermis, and the flat papule was that of verwca plana. Bone marrow aspirate was essentially normal. Primary cutaneous plasmacytoma is a rare disease. A significant proportion of patients with this ent on to develop systemic disease with a poor prognosis. Our patient was not treatead, bit only excised partially for biopsy. All skin lesions involuted two years later spontaneously and rema ns well until now six years later without recurring.

A Case of Cerebriform Intradermal Melanocytic Nevus / 대한피부과학회지

Cerebriform intradermal melanocytic nevus is a cause of cutis veticis gyrata, a morphologic term which describes the hypertrophy and folding of the skin, typically occurring on the scslp, to present a gyrate or cerebriform appearance. We report a 37-year-old woman with a 17 x 22cm soft, convoluted mass over most of the occipital, parietal, and temporal scalp. At birth, she had a small brownish macide on the occipital scalp that enlarged to form this extensive lesion. Histologically, nests of nevus cells were shown in the upper and the mid dermis.

Dyschromatosis Universalis Hereditaria / 대한피부과학회지

Dyschromatosis universalis hereditaria is a rare pigmentary disorder characterized by widespread mothed hyperpigmentation and hypopigmentation. We report a 40-year-old male patient with numerous hyperpigmenter, and hypopigmented macules all over the body except on the palms and soles. The family history revealed similar pigmentary changes in 5 other members through 4 generations, and we could guess the hereditary pattern of the disease of this family to be autosomal dominant inheritance.

A Case of Ichthyosiform Sarcoidosis / 대한피부과학회지

Although acquired ichthyosis has been associated with a number of systemic illnesses, an association with sarcoidosis has rarely been reported. We report a patient with aquired ichthyosis of the lower and upper extrimities whose diagnosis of cutaneous sarcoidosis was confirmed by histologic examination. Systemic involvement in the patient revealed occular, pulmonary and nerve disease. A diagnosis of sarcoidosis must be considered when a patient presents with acquired ichthyosis.

A Case of Granulomatous Perioral Dermatitis / 대한피부과학회지

A 51-year-old female developed a distinctive perioral rash, conisting of discrete or confluent erythematous papules for one and a half years. Histopathologic examiriation revealed upper dermal granulomas admixed with lymphoytes. Pieces of hair shaft were staincd peri-dish by AFB in the center of granuloma, which might play a role in the formation of the granuloma She also had used corticosteroid ointment intermittently duririg this time. There were no associated systemic abnormalities. The lesions resolved after two month treatment with oral corticosteroid and tetrac cline.

A Case of Lichen Aureus / 대한피부과학회지

A case report of a 60 year-old man with lichen aureus of leg is presented. Clinically the solitary golden to purple colored patch consists of lichenoid papules, plsque, and mild petechiae around the lesion, and the histology reveals a dense and bandlike infiltrate hugging thepidermis. It consists of lymphocytes, histiocytes, eosinophils, and many extravasated erythrocytes and hemosiderin in dermis, but a few red cells and increased melanin pigment can also be seen in the epidermis. The eruption is mildly itchy and has been present 6 months.

Two Cases of Basal Cell Carcinoma Occurring on Male and Female External Genitalia / 대한피부과학회지

Basal cell carcinoma(BCC) is the most common human malignancy. It involves the face and neck most frequently. However, BCC can very rarely occur on external glenitalia such as scrotum and vulva. We report two cases of serotal and vulvar BCCs in a 67 year old imale and a 43 year old female. He suffered from well defineril erythematous to violet colored plaque with central erosion on the left scrotum for 5 years. She had a brown black colored plaque on the left vulva for 8 years. They did not show any metastatic foci from g!rimary cutaneous lesions, and underwent surgical excision and curettage respectively.

Clinical Study of Scabies for 15 Years / 대한피부과학회지

Human sparganosis is not uncommon and over 60 cases are reported in Korea but the case infested with multiple spargana is rare. The case we are reporting here is a 33 year-old Korean male having had an abscess and several bean-sized nodules on the left thigh. The patient had the history of eating frogs as a tonic food 3 years ago. Five spargana were removed from the lesions by surgical excision. Two of them were alive and other three were degenerated or calcified.

A Case of Mutiple Leiomyoma Cutis / 대한피부과학회지

Leicmyomas represent benign painful tumor principally derived from cutaneous smooth muscle. The majority of these lesions arised from arrector pili muscles, the media of blood vessels, or smooth muscle of scrotum, labia majora, and nipples. Cutaneous leiomyomas may be solitary or rnultiple and generally present as pink, red or dusky brown firm derrnal nodules of varying sizes. We present a case of multiple leiomyoma cutis in a 44-year-old male. The skin lesions were characterized clinically by numerous, miliary to bean sized, reddish brow papules and nodules on the both shoulders, right arm, right side of the neck, upper chest, and upper back, which were pinful by pressure. The histopathologic examination revealed interlacing bundles of the smooth muscle fibers in the dermis, slight atrophy of epidermis, and a grenz zone of normal corium hetween the epidermis and the tumor.

Two Cases of Linear Lichen Simplex Chronicus / 대한피부과학회지

We present two cases of linear lichen simplex chronicus. One is a 44-year-old male patient who had a linear licbenified patch on the left upper extremity, and the other is a 45-year-old female patient who had linear pruriginous nodules on the right lower extremity. The one is coincidental with localized lichen simplex chronicus, the other is coincidental with prurigo nodularis histopathologically.

A Case of Cystic Hygroma / 대한피부과학회지

Cystic hygroma, or cystic lymphangioma, is a true, benign, congenital rnulticystic tumor arising from sequestrations of embryonic ly mphatic iissue. Most often it occurs. At birth or early in life, and it is found most commonly in the neck, and its distribution coincides with that of the prirnitive lymph sacs. We report herein a case of huge cystic hygroma on the face and neck in a 2 month-old male infant. The swelling was softly cystic, and was partially compressible, and it was brilliantly translucent. The cystic mass contained a serous fluid. Biopsy findings showed simple endothelium-lined lymphatic vessel and loose, lace-like fibrous tissue stroma, and dilated muscle space filled with serous fluid.

A Case of Xanthoma Tuberosum in Type II Hyperlipoproteinemia / 대한피부과학회지

A 22-year-old male has had multiple, grouped, asymptomatic, yellowish flat papules, nodules, and plaques on the knees, elbows, butteeks, hands, and feet. Yellowish nodules first appeared on the heels after birth, and gradually increased in size and number and spread to the knees, elbows, buttocks, and hands. Physical examination revealed normaI except for the skin lesions. Gross finding of the serum was clear and paper electrophoresis revealed marked increase in betalipo-protein and mild increase in prebetalipoprotein, suggesting type II hyperlipoproteinemia Serum cholesterol was 510 mg%, and serum triglyceride was 190mg%. Histopathology showed many aggregates of foam cells on H-E stain and many lipid droplets in the dermis on oil red O stain.