[Prevalence of obesity, abdominal obesity and hypertension in 10-13 years old children of governmental and non-governmental elementary school in some regions of Tehran in 1390 year]

Obesity and hypertension disorders affect whole body and are associated with most diseases, including diabetes and cardiovascular disease. Children with obesity and high blood pressure are prone to adulthood health problems. Yet most parents are unaware of their child obesity and high blood pressure. This 2011 study, included 1184 boys and girls aged 10-13 years old from five districts of Tehran. Overweight and obesity were diagnosed by the International Obesity Task Force [IOTF] criteria. Also, systolic or diastolic blood pressure >/= 95 for age, height and gender were considered as hypertensive. Waist circumference according to the standard Iranian cut off for children was assessed on the basis of age, gender. Waist circumference > 90 percentile was considered as abdominal obesity. Prevalences of overweight, obesity, hypertension and abdominal obesity were 21.92, 5.28, 13.16 and 25.31% respectively. The highest prevalence of obesity and abdominal obesity reported in District 3, which is north of Tehran and the lowest was related to boys from region 19 of southern Tehran. Economic conditions can affect obesity and hypertension disorders and more attention must be paid to obesity and hypertension in particular, to creat awarences in parents for changes in lifestyle, nutrition and physical activity these children

[Effect of coenzyme Q10 on neuropathic pain in adult CCI Rat model]

Oxidative stress is known as the one of the causes of neuropathic pain, reactive oxygen species [ROS] has been reported to be involved in this process. Coenzyme Q10 acts as an antioxidant and is able to reduce resulting oxidative damage. This study was done to determine the effect of Coenzyme Q10 on neuropathic pain in CCI [Chronic Crash Injury] rat model. In this experimental study 30 male rats [200-250g] randomizely allocated into 3 groups each 10 rat including CCI, CCI+CoQ10 and CCI+vehicle. Neuropathic pain, was induced by Chronic Crash Injury [CCI] model for sciatic nerve. IP injection of CoQ10 [200 mg/kg] or vehicle was done daily for 10 days. Behavioral tests were done before and after surgery on day 5 and 10 respectively. Paw withdrawal threshold was assessed by Randall Selitto test, Analgesy Metter and Von Frey filaments. Data was analyzed by SPSS-14, Independent T and Mean-whatney tests. Induction of nerve injury decreased pain threshold [P<0.05] and treatment with CoQ10 increased mechanical and thermal threshold in neuropathic rats compared to CCI animals [P<0.05]. There was a significant difference in pain threshold between animals treated CoQ10 and vehicle injected animals [P<0.05]. This study indicated that coenzyme Q10 prevents deleterious effects following nerve injury in animal model