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1.
JLUMHS-Journal of the Liaquat University of Medical Health Sciences. 2017; 16 (1): 49-52
en Inglés | IMEMR | ID: emr-189503

RESUMEN

Introduction: Myeloid malignancies are clonal disorders of hematopoietic stem/precursor cells. The criteria for the diagnosis of acute myeloid leukemia [AML] are based on morphological cytogenetic and flow-cytometric findings. The prognostic outcome with intensive chemotherapy is better than with non-intensive treatment


Purpose/Objectives: To determine the frequency of various clinical and pathological findings in myeloid malignancies


Study Design: Cross sectional descriptive study


Place and Duration of Study: The study was carried out at Department of Pathology from October 2014 to December 2016


Material/Patients and methods: Detailed history, clinical and pathological findings recorded on a pre-designed proforma including bone marrow reports was evaluated


Results: During period of study, 351 proformas including bone marrow reports were evaluated, from which 49 [30 males and 19 females; age ranges between 03 months to 60 years] were diagnosed as myeloid malignancies. The distribution of myeloid malignancies were acute myeloid leukemia [n=21], chronic myeloid leukemia [n=14], acute myelodysplastic syndrome [n=3], myeloproliferative neoplasms [n=3], myelofibrosis [n=2], myeloid hyperplasia [n=2], acute promyelocytic leukemia [n=2], myelomonocytic leukemia [n=1], ,and transient abnormal myelopoiesis [n=1].The main presenting complaints were fever and weight loss, whereas splenomegaly was the most common finding on clinical examination. The commonest laboratory finding was anemia followed by leukocytosis; while 10 patients showed pancytopenia


Conclusion: AML with fever and bicytopenia is the commonest myeloid malignancy in our series

2.
JLUMHS-Journal of the Liaquat University of Medical Health Sciences. 2015; 14 (1): 33-37
en Inglés | IMEMR | ID: emr-192253

RESUMEN

To evaluate the short term results of open reduction and internal fixation with cross k-wires in type III supracondylar fracture of Humerus in children in our setup


PATIENTS and METHODS: This prospective study was conducted at Department of Orthopaedic Surgery and Traumatology, Liaquat University of Medical and Health Sciences, Jamshoro from March 2012 to March 2014. Total forty-seven patients with type III supracondylar Fracture Humerus were evaluated in this series. All were treated with open reduction and internal fixation with cross k-wires. The children followed regularly and the cosmetic and functional results assessed according to the Flynn criteria


RESULTS: The mean age in our series was 7.4 years. There were 35 boys and 12 girls


The most common mode of injury 72.34% was fall during play. In 95.75% of our cases injury was extension type and in 4.25% flexion type. Grade I pin tract infection was noted in only 3 patients. 69% cases have excellent cosmetic and functional results, 22% were having good cosmetic and functional results according to Flynn Criteria


CONCLUSION: Open reduction and internal fixation with cross k-wires produce excellent to good results in Gartland type III supracondylar fracture especially in the areas where image intensifier facilities are limited

3.
JLUMHS-Journal of the Liaquat University of Medical Health Sciences. 2011; 10 (3): 134-137
en Inglés | IMEMR | ID: emr-194809

RESUMEN

Objective: The purpose of this study was to evaluate the results of dynamic condylar screw system in the management of subtrochanteric femoral fractures, regarding union time, implant failure rate; infection rate and functional out come


Study Design: A prospective case series


Place and duration of study: This study was carried at the department of Orthopedic Surgery and Traumatology Liaquat university of Medical and Health, sciences Jamshoro, during January 2008 to December 2009


Material and Methods: Total 52 consecutive patients with subtrochanteric fracture were studied .Four patients were lost during follow-up and total 48 patients were finally assessed. The inclusion criteria was closed subtrochanteric fractures in adults of both gender aged 20 years or above; pathological fractures and open fractures were excluded from the study. After fixation of fractures with dynamic condylar screw system patients were followed -up for 6-12 months, the mean follow up period was 8 months. Results of treatment were assessed by the Radford criteria


Results: Among 48 studied cases, males were 29[60.42%] and female 19[39.58%]. Most common mode of injury was road traffic accidents in 32 patients [66.66%] and 16 patients had fall. All the patients underwent operative treatment by fixation of DCS. Autogenous bone graft was done in 07 patients. The union rate in this series was [93.5%]. Implant failure was observed in 03[6.25%] patients, 03 [6.25%] patients developed varus deformity and infection occurred in 02 [4.66 %]. According to criteria of Radford, we achieved good to excellent results in 81 % cases, fair in 6 [12.5 %] patients, poor in 03[6.25%0] patients


Conclusion: We conclude that subtrochanteric fractures need open reduction and internal fixation to avoid complications like implant failure, nonunion, infection, and mal-union. In our circumstances we achieve good results by the use of dynamic condylar screw

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