effects of some prostaglandin synthesis inhibitor drugs on serum glucose and insulin levels in diabetic patients

The effect of conventional doses of prostaglandin synthesis inhibitors [FGSIS] on serum glucose and insulin levels was studied in 30 diabetic patients. The results show that treatment with aspirin [one gram tds] for three days did not cause a significant change in fasting serum glucose and insulin levels, but it caused a significant drop in serum glucose and elevation in serum insulin following glucose load. Mefenamic acid [250 mg tds] given for three days did not alter significantly the fasting serum glucose or insulin and it did not change the serum glucose or insulin levels following glucose load. Diclofenac [25 mg tds] given for three days again did not alter fasting serum glucose or insulin and it did not affect significantly the serum glucose or insulin levels following the glucose loads

Effects of bees honey, zahdi date and its syrup on blood glucose and serum insulin of normal subjects

Postprandial glycemia and rise in serum insulin after bees honey, zahdi dates and zahdi date syrup, were compared with those after glucose alone and with mixtures of sugars having the same ratio found in honey and syrup; in 21 healthy volunteers. In the honey-study group [10 subjects], the lowest level of blood glucose was after honey, while the level after F.G.S. was not significant in comparison to the levels after glucose and honey. In the syrup-study [9 subjects], the lowest level of blood glucose was after the syrup followed by the F.G. mixture and lastly after glucose. On the other hand there was both a gradual rise and declination after date [12 subjects], with a much lower level than after glucose. - The serum insulin responses after honey and syrup, and their corresponding mixtures were lower than after glucose alone. In the meantime, the two mixtures F.G.S. and F.G. caused a significant higher level of serum insulin than glucose alone at the end of the test period. The serum -insulin after dates was significantly lower than after glucose in the first half of the test period, but higher at 120 mm. Interval