RESUMEN
Background: Polycystic ovary syndrome [PCO] is one of the most common reasons for infertility. Calligonum as a plant possess some of the important antioxidants that can decrease oxidative stress
Objective: The effects of treatment with Calligonum as an antioxidant on ovary tissue of a PCO mouse model
Materials and Methods: Thirty female NMRI mice were divided into three groups [n=10/each]: control, PCO, and Calligonum. We induced PCO model with single dose of Estradiol valerate [40 mg/kg]. Then Calligonum [20 mg/kg] was intraperitoneally injected weekly for two months. The level of oxidative stress and total antioxidant capacity was assessed in the ovarian tissue by flow cytometry and fluorescence recovery after photobleaching, respectively, and the histological study was conducted by the morphometric method and embryo development with in vitro fertilization
Results: The obtained results showed that estradiol valerate was able to increase oxidative stress within the ovary and causes ovarian cysts after two months. The cyst formation was decreased in Calligonum group compared to PCO group [p=0.001]. The percentage of pre-antral and antral follicles significantly decreased in Calligonum group compared to PCO group [p=0.001]. The oxidative stress decreased in Calligonum group significantly compared to PCO group [p=0.001]. Calligonum can significantly increase the total antioxidant capacity of ovarian tissue [p=0.001] as well as the percentage of in vitro fertilization compared to the PCO group
Conclusion: Calligonum could decrease ovary cyst in PCO model, and improve in vitro fertilization rate. Also, Calligonum extract as an antioxidant could decrease oxidative stress in PCO model
RESUMEN
Introduction: Nose morphology depends on gender, ethnicity, and environmental conditions. It can be used in identification of the race and sex of persons whose identity is unknown. Nasal index is a useful tool in anthropometry
Methods: In this study, nasal parameters of Iranian males and females students were measured [nasal height, nasal width, and nasal index]. This study was conducted on 200 medical students of Tehran University, Tehran, Iran. Subjects were 100 males and 100 females, aged 18-30 years. The nasal height and width were measured by a sliding vernier calliper and the nasal index was accordingly calculated
Results: Our data showed that the mean nasal index for males and females were 68.91 +/- 8.11 and 66.05 +/- 7.53, respectively. So, nose of Iranian people is leptorrhine type. The mean nasal index in males was significantly [P and le,0.05] higher than that in females
Conclusion: The result of this study could be employed in the detection of gender in forensic medicine and rhinoplasty surgery