RESUMEN
Three women on chloroquine therapy, two 58-and 61-year-old, with rheumatoid arthritis, and one, 62-year-old, with systemic lupus erythematosus developed ocular complications. One patient developed cornea verticillata-like deposits in her corneas, which did not affect her sight. Two patients developed irreversible visual loss and showed typical [bull's eye] lesions in the central retina. The discontinuation of drug led to clearance of corneal deposits but did not effect the visual and retinal changes. Regular ocular examinations during chloroquine [or its derivatives] therapy are essential. The careful evaluations of visual acuity, visual fields, color vision [blue-yellow dyschromatopsia], and electrooculogram are helpful in the early detection of chloroquine toxicity