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Rev. méd. Chile ; 150(2): 199-205, feb. 2022. tab
Artículo en Español | LILACS | ID: biblio-1389644

RESUMEN

BACKGROUND: 18F-fluorodesoxyglucose positron emission tomography/ computed tomography (PET-CT) has a high sensitivity and specificity to detect medullary and extramedullary lesions in multiple myeloma (MM). AIM: To describe the findings of PET-CT in extramedullary multiple myeloma (EMM) at diagnosis and at relapse, and correlate its results with clinical variables, response to treatment and survival. MATERIALS AND METHODS: Review of medical records and PET-CT reports of 39 patients with multiple myeloma (MM) who had at least one PET-CT study, treated between January 1, 2015, and January 1, 2019 at a clinical hospital. RESULTS: The Standard Uptake Values for each hypermetabolic lesion were not described in PET-CT reports. Fifteen patients had an EMM and in eight, without a previous clinical suspicion, PET-TC lead to the diagnosis. The mortality rate in the 39 patients with MM was 46%. Sixty seven percent of deaths occurred in patients with EMM. CONCLUSIONS: PET-TC was useful to diagnose EMM. However, a standardization in PETCT reports would be required to unify criteria. As previously reported, EMM had a greater aggressiveness and lower survival.


Asunto(s)
Humanos , Tomografía Computarizada por Tomografía de Emisión de Positrones/métodos , Mieloma Múltiple/tratamiento farmacológico , Mieloma Múltiple/diagnóstico por imagen , Radiofármacos , Fluorodesoxiglucosa F18 , Tomografía de Emisión de Positrones/métodos , Recurrencia Local de Neoplasia
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