RESUMEN
Objective: To study the secondary metabolites of endophytic fungus Chaetomium sp. Methods: The compounds were isolated and purified by chromatographic methods on silica gel, Sephadex-LH20 columns, and semi-prep HPLC. The structures were established on the basis of spectroscopic data interpretation. Results: Ten compounds were isolated and identified as chetoseminudin B (1), gonytolide C (2), chaetone D (3), 1H-indole-3-carbaldehyde (4), 1H-indole-3-carboxylic acid (5), indole-3-methylethanoate (6), 3R*,4R*-dihydroxy-3-methylpentan-2-one (7), emodin (8), 3β,5α,9α-trihydroxy-(22E,24R)-ergosta-7,22-dien-6-one (9), and (3β,5α, 6β,22E)-6-methoxyergosta-7,22-diene-3,5-diol (10). Conclusion: All compounds are isolated from Chaetomium sp. for the first time.
RESUMEN
OBJECTIVE: To study the chemical constituents of Sapium sebiferum leaves. METHODS: The chemical constituents in the petroleum ether and n-butyl alcohol parts of the 95% ethanol extract of Sapium sebiferum leaves were isolated and purified by chromatographic methods. Their structures were elucidated by spectral data and physicochemical properties. RESULTS: Twelve compounds were purified and identified as squalene(1), 3β-hydroxyglutin-5-ene(2), fraxetin(3), friedelin(4), β-sitosterol(5), gallic acid ethyl ester (6), quercetin (7), 5-hydroxymethylfurfural (8), blumenol C glucoside (9), kaempferol-3-O-β-D-glucopyranoside (10), 1'-O-benzyl-α-L-rhamnopyranosyl-(1″-6') -β-D-glucopyranoside(11), and shikimic acid(12). CONCLUSION: Compounds 1-3, and 8-12 are isolated for the first time from this plant.