Fetal neck myofibroma.

Magnetic resonance imaging (MRI), as an adjunct to ultrasonography, has become a promising tool in prenatal diagnosis and therapy. In this report, the authors described a case of giant solid mass arising in the fetal neck region diagnosed by prenatal sonographic examination at the gestational age of 33 weeks'. MRI was used to confirm the diagnosis, and to assist fetal airway assessment. Due to the concern of fetal airway compromise, the ex utero intrapartum treatment (EXIT) was strategically planned with help from specialists in the according fields. This allowed the authors to secure the fetal airway before fetomaternal circulation was disconnected. It was performed successfully through Cesarean section at the time of birth. Histopathology revealed infantile myofibroma, which is a rare form of such a tumor arising on the fetal head and neck region diagnosed prenatally.

Subtle finding analysis in false negative results on screening mammogram and US: An institute study.

Objective: To determine the percentage and evaluate the subtle findings of false negative results on mammogram and ultrasonography (US) screening. Methods: A retrospective study involved twelve breast cancer patients who had a negative result of malignancy on both the initial mammogram and US with an equal number of benign or negative cases mixed. One radiologist randomly reviewed all mammograms and US images without any knowledge of the final diagnosis, noting mammographic characteristics of breast density composition, lesion type, size, and morphology according to (BIRADS-LEXICON). Results: The incidence of prospectively false-negative rates was 7.3% (7 of 9,582). The type of subtle findings characterized on the prior mammogram included a macrolobulated mass in one of seven lesions (14.3%), a macrolobulated mass with amorphous microcalcification in one (14.3%), amorphous microcalcification alone in one (14.3%), and asymmetrical breast density on one-view mammogram in two (28.6%). There were two of seven lesions with negative mammogram and positive US findings. Conclusion: There is a small subset of breast cancer, called subtle findings, which can be perceptible but sometimes there are no definite malignant findings on the image interpretation. An understanding of the characteristics of subtle findings in false-negative screens may be a valuable aid in increasing the sensitivity of breast cancer detection.

Interval cancer in mammogram screening: Incidence and diagnostic value of additional ultrasonography in Thai women.

Objective: The purpose of this study was to characterize the mammographic and ultrasonographic ( US) findings in interval cancer and to evaluate incidence and additional diagnostic value of US in interval breast cancer. Methods: A retrospective study involved three women who had negative results in both screening mammogram and US within 18 months before a diagnosis of breast cancer. The mammographic and US findings were classified according to Breast Imaging Reporting and Data System, categories 0-5. The method of detection, tumor histologic grade, axillary node status and tumor size were analyzed. Results: The interval cancer incidence in our institute was 3.14 per 10,000 screens. Three interval cancers were found. All patients had heterogenous dense breasts. Two of the three interval cancers could only be identified by US. All of them were invasive cancer with a high-to-intermediate grade (grade 2-3). Conclusions: Adjunctive US is noninvasive and valuable a modality for detection and characterization of interval cancer.