Analog experiment of transarterial catheter hyperthermic infusion in vitro / 介入放射学杂志

Objective To investigate the factors related to the heating effect by transarterial catheter hyperthermic infusion with the evaluation of the feasibility in controlling the tumor temperature.Methods Infusing 55-68℃ liquid at the speed of 10-40 ml/min through 6F,5F or 3F catheter with different length respectively under the similar clinical condition.The liquid temperature at the terminal exit of the catheter was measured with a digital thermometer.The factors related to the liquid temperature at the exit of the catheter were analyzed by multiple regression analysis. Results The infusion temperature,rate and the catheter length were the main related factors to the liquid temperature at the exit of the catheter as the condition similar in clinical use.When 60-65℃ liquid was infused at the rate of 20-40 ml/min through 5F catheter with length of 80 cm,the mean and 95% confidencial interval of the liquid temperature at the chetheter exit were(47.55?0.44)℃ and 44.61-48.49℃ respectively.Conclusions The liquid temperature at the exit of infusion catheter can be regulated and controlled through adjusting the liquid perfusion temperature and speed.

Dynamic change of T-lymphocyte subsets in patients with liver cancer treated by intra-arterial hyperthermia chemoembolization / 介入放射学杂志

Objective To investigate the dynamic change of T-lymphocyte subsets in the patients of liver cancer treated with intra-arterial hyperthermia chemoembolization (IHCE). Methods Sixteen patients of hepatic cancer were treated with IHCE. One or two weeks before and after the procedure, the blood samples were collected for evaluation of the peripheral blood T-lymphocyte subsets using flow cytometry in 16 cases. The results were compared with those of other 18 patients received routine transcatheter arterial chemoembolization (TACE) during the same period. Results The cases of IHCE group showed that the proportion of CD4 cells was increased and that of CD8 cell was decreased after 2 weeks of the treatment, so that the ratio of CD4 to CD8 was obviously higher than that of the control group (P=0.01). Conclusion The hyperthermia effect of IHCE can further enhance immune function of the patients with liver cancer.

Clinical study of intra-arterial hyperthermia chemoembolization combined with Tween-80 for treatment of metastatic hepatic carcinoma / 介入放射学杂志

0.05). Conclusions Transcatheter arterial thermochemoembolization combined with hepatic arterial infusion of Tween-80 is an effective and safe method in treating metastatic hepatic carcinoma.