RESUMEN
Platelet rich plasma (PRP) therapy has been growing in popularity as a viable treatment alternative for a number of clinical applications and has a potential benefit for use in wound healing. The objective of the present study was to verify the effectiveness of PRP in the management of the refractory cutaneous ulcer associated with Nicolau syndrome. A 73-year-old woman with a diclofenac sodium intramuscular injection history in a local clinic presented with a severely painful acute necrotic ulcer on the right buttock. The ulcerative wound showed no improvement despite having conventional treatment for 1 month. After 3 weeks of the PRP treatment, the wound evolved favorably, with the alleviation of severe pain. It showed a size reduction of more than 80% after 4 months of regular follow up. The result demonstrated that PRP treatment could be an appropriate option for an extensive refractory ulceration associated with Nicolau syndrome.
Asunto(s)
Femenino , Humanos , Plaquetas , Nalgas , Diclofenaco , Estudios de Seguimiento , Inyecciones Intramusculares , Plasma Rico en Plaquetas , Úlcera , Cicatrización de HeridasRESUMEN
Phacomatosis pigmentokeratotica (PPK) is a rare syndrome defined by the association of an organoid nevus occasionally with sebaceous differentiation, a speckled lentiginous nevus, and other extracutaneous anomalies. A preterm male infant of only 830 g at 27 week gestational age had an organoid nevus showing sebaceous differentiation. Also, he had multiple speckled-lentiginous nevus. Correlating the observed clinical presentation with the histopathological findings, the diagnosis of PPK was established. There have been less than 10 cases of PPK without extracutaneous manifestation. We present an uncommon case of a preterm patient with PPK who had no extracutaneous abnormalities.