RESUMEN
The last stage of many hepatic diseases, including hepatitis, is cirrhosis. The liver's vital function in detoxifying xenobiotics—such as medications and toxic composites—is the subject of much research. Liver cirrhosis is the cause of alterations in the liver's architecture that mostly affect protein binding, blood circulation, and the enzymes that break down medicinal substances. The main reason why therapeutic metabolising enzymes disappear is because to liver towel loss. However, not all enzyme activity is decreased in tandem; some are only changed in one specific case. This case report focuses on the clinical features, diagnostic evaluation, and therapeutic concerns of a patient having liver cirrhosis. Further research and advancements in our comprehension of the pathogenesis and treatment of cirrhosis are necessary in order to enhance outcomes and minimise the burden of this illness on those who are impacted.
RESUMEN
Chiari II malformation (CM-II) is an innate CNS condition in which the medulla oblongata, pons, fourth ventricle, and cerebellum move lower inside the spinal canal. This abnormality is one of the leading causes of neonatal and infant death. The diagnosis of CM-II in the patient necessitates a thorough understanding of the findings. In this case report, we demonstrate a Chiari malformation II identified by MRI of the brain and spine. This case also highlights the need for neuropsychological evaluation in CM-II in terms of providing guidance for psychoeducation and psychotherapy.
RESUMEN
Osteoarthritis, also known as OA, is a type of joint degeneration characterized by changes in the morphology and biochemistry of the synovial membrane and joint capsule, as well as degradation of cartilage joint and expansion of the marginal bone. Inflammation causes the joints to deteriorate in a subtype of osteoarthritis called erosive OA. DIP (distal interphalangeal), PIP (proximal interphalangeal), CMC (carpometacarpal) and metacarpophalangeal (MCP) joints are the most often affected joints in the hand. Other joints in other body regions are extremely seldom affected. Our patient’s diagnosis report suggests erosive osteoarthritis and seronegative arthritis as negative anti-RF factors.