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Indian J Lepr ; 1992 Oct-Dec; 64(4): 475-81
Artículo en Inglés | IMSEAR | ID: sea-54568

RESUMEN

Dissemination of M. leprae to visceral organs is seen by four months onwards only in beige (C57BL/6/bgj) but not BALB/c mice following intravenous or intraperitoneal infections. Inoculation of the beige mouse derived M. leprae showed all the characteristics of M. leprae, including growth pattern in the foot-pads of BALB/c mice. M. leprae inoculated into foot-pads of beige mice multiplied faster than those in the foot-pads of BALB/c mice. The possibility of using beige mouse in chemotherapeutic studies in leprosy is discussed.


Asunto(s)
Animales , Modelos Animales de Enfermedad , Femenino , Lepra/microbiología , Hígado/microbiología , Ratones , Ratones Endogámicos BALB C , Ratones Endogámicos C57BL/microbiología , Mycobacterium leprae/crecimiento & desarrollo , Bazo/microbiología
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