Serum concentration of testosterone, epididymal mast cell population and histamine content in relation to sperm count and their motility in albino rats following H2 receptor blocker treatment.

H2 receptor blocker treatment over a period of 2 weeks had been found to cause significant reduction in epididymal tissue mast cell population and tissue histamine content in caput, corpus and cauda regions in albino rats. There was also a highly significant fall of serum testosterone level and sperm count in these segmental fluids collected by micropuncture. The motility of sperms was also greatly reduced and the number of abnormal spermatozoa was found to be increased, the increase being highly significant in the caudal segment. In view of histamine being involved in steroidogenic activity, it appears that reduction in epididymal tissue histamine content following H2 receptor blocker treatment had caused low availability of testosterone to the tissues and thereby the reduction in sperm count and their motility. Increase in number of abnormal sperms particularly in the caudal epididymis is likely to be due to malformation and increased destruction of sperms, because of alteration in epididymal environment due to fall in serum testosterone concentration.

Effect of application of gyrosonic waves through brain on arthritic pain and migrainous headache.

Gyrosonic waves created by placing the recorded sound waves on an oscillating frequency device has been utilized to alleviate long-standing pain in patients suffering from arthritis of various types and in migrainous headache. It was interesting to observe that arthritic pain had disappeared totally or there was about 80 to 90.0% reduction with planned installation of gyrosonic waves through headphone. Individuals with a long history of migrainous headache also had complete relief after a few installations; it appears that gyrosonic waves would be of immense help for the treatment of pain due to aforesaid problems.