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Indian J Physiol Pharmacol ; 1994 Jul; 38(3): 220-2
Artículo en Inglés | IMSEAR | ID: sea-106760

RESUMEN

A Leucodelphinidin derivative isolated from the bark of Ficus bengalensis Linn demonstrated hypoglycemic action at a dosage of 250 mg/kg given both in normal and alloxan diabetic rats. It's action is closely similar to that of an effective dose of glibenclamide (2 mg/kg) tested under the same conditions. However, after a glucose load the plant product is only just significantly active but not as effective as the sulphonylurea. The efficacy of the plant product as a hydroglycemic agent adds to its other therapeutic effects, as it belongs to the class of flavonoids.


Asunto(s)
Animales , Glucemia/efectos de los fármacos , Diabetes Mellitus Experimental/tratamiento farmacológico , Flavonoides/aislamiento & purificación , Prueba de Tolerancia a la Glucosa , Gliburida/farmacología , Hipoglucemia/inducido químicamente , Extractos Vegetales/farmacología , Ratas
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