Fever of unknown origin in carcinoma of the colon

To report a case of fever of unknown origin in a patient with carcinoma of the colon but without gastrointestinal symptoms. Clinical Presentation and Intervention: A 65-year-old man presented with a long-standing fever [of 38°C, about two months' duration], night sweats, fatigue, malaise and anxiety. General physical examination including rectum, radiographic examinations of the chest, abdomen and bones [including ultrasonography and CT scanning] was normal. Biochemistry profile as well as other laboratory studies including blood, urine and stool cultures were normal except for erythrocyte sedimentation rate, which was 105 mm/h. A barium enema showed a rectosigmoid carcinoma. A left sigmoidal colectomy was performed. The patient recovered quickly and remained well for eight years postoperatively. This case shows that carcinoma of the colon should be included in the differential diagnosis of patients with fever of unknown origin

Treatment of ureteral colic with diclofenac sodium

The efficacy of diclofenac sodium, a potent inhibitor of prostaglandin synthetase, was compared with the efficacy of a spasmolytic agent, hyoscine butylbromide, in the treatment of 78 patients [53 men and 25 women] suffering from acute ureteral colic. Forty-two patients [group A] received diclofenac sodium intramuscularly and 36 [group B] hyoscine butylbromide intramuscularly. Both groups were comparable for weight, age and sex. Diclofenac sodium relieved the colic effect in 38 out of 42 patients [90%] within 30 min after the injection and 7 of 36 patients in the hyoscine butylbromide group [19%]. In 4 patients of group A, a second injection of diclofenac sodium, given 30 min later, completely relieved the pain within 30 min. In group A, side effects, such as nausea, vomiting, and headache, occurred in 4 patients. In conclusion, diclofenac sodium, administered intramuscularly, is more effective in treating ureteral colic than hyoscine butylbromide and has fewer side effects