Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Añadir filtros








Intervalo de año
1.
Clinics ; 65(10): 1037-1042, 2010. ilus, tab
Artículo en Inglés | LILACS | ID: lil-565991

RESUMEN

INTRODUCTION: We investigated the antianxiety and sedative effects of the essential oil of Ducrosia anethifolia. Boiss. (Apiaceae). METHODS: We used elevated plus maze, spontaneous motor activity and ketamine-induced sleep tests in mice. In addition, the essential oil was analyzed by GC/MS. Twenty compounds were identified, and n-decanal (70.1 percent) and alpha-pinene (12.4 percent) constituted the major components. RESULTS: In elevated plus maze, Ducrosia anethifolia essential oil at doses of 25-200 mg/kg increased the percentage of open arm time and entries. Unlike diazepam, ducrosia anethifolia essential oil could not suppress spontaneous motor activity and did not alter ketamine-induced sleep parameters. These results are indicative of antianxiety effect of Ducrosia anethifolia essential oil without sedative effect.


Asunto(s)
Animales , Masculino , Ratones , Ansiolíticos/efectos adversos , Hipnóticos y Sedantes/efectos adversos , Aprendizaje por Laberinto/efectos de los fármacos , Actividad Motora/efectos de los fármacos , Aceites de Plantas/efectos adversos , Plantas Medicinales/efectos adversos , Sueño/efectos de los fármacos , Análisis de Varianza , Modelos Animales , Aceites de Plantas/administración & dosificación , Aceites de Plantas/química , Plantas Medicinales/química
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA