Castleman's disease in a 35 year-old woman with a giant mediastinal mass

The patient was a 35 year-old woman with a 10-month history of breathing difficulty, cough and chest pain. An anterior-posterior chest radiograph revealed opacification of the right hemithorax with reduced right lung volumes. As part of diagnostic evaluation, a computed tomography [CT] scan was performed which showed a huge mass in the right anterior mediastinum with extension to the right side of the pleural space. It was resected through postero-lateral thoracotomy. The patient was discharged in a good condition. The pathology report showed hyaline vascular variant of Castleman's disease