RESUMEN
The alpha-2 adrenergic receptor (?-2 AR) agonists have a long history of use in treating different clinical conditions, such as hypertension, psychiatric entities (e.g., attention-deficit hyperactivity disorder), chronic pain, panic disorders, and, lately, for treating opioid withdrawal syndrome. In recent years, ?-2 AR medications have been administered as adjuncts for managing inflammatory conditions, depression, chronic pain, sleep and cognitive disorders. This review will provide some clinical applications in neuroscience for this class of drugs. Understanding the pharmacological mechanisms is essential to obtaining neurochemical data that demonstrate that ?-2 AR agonists have potential clinical significance in neuroscience.
RESUMEN
Cuando ocurre un prolapso rectal masivo el cirujano cuenta con multiples tecnicas para su tratamiento y debe elegir la mejor.Se presentan los resultados de ocho enfermas a las que se les trato con rectopexia presacra empleando una banda de mersilene o silastic, con tecnica similar a la descrita por Ripstein, que corrige la curvatura del recto al fijarlo a la fascia presacra. Desde el postoperatorio inmediato observamos reduccion del prolapso. Una paciente anciana fallecio por problemas cardiopulmonares una semana despues de la intervencion; las otras siete tienen continencia anal y no han requerido de otras intervenciones en un periodo de 3 a 6 ano