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J Indian Med Assoc ; 1999 Jan; 97(1): 6-7
Artículo en Inglés | IMSEAR | ID: sea-97558

RESUMEN

A case-control study was carried out on patients of myocardial infarction selected from coronary care unit of Lok Nayak Jai Prakash Narayan Hospital, Delhi. The study was carried out to determine the association of haptoglobin (Hp), transferrin (Tf) and complement component 3 (C3) polymorphism with myocardial infarction. The frequency of allele Hp1 was found to be 0.159 in cases studied and 0.058 in controls. The frequency of gene TfC was found to be 0.987 in cases of study and 0.992 in controls. Similarly, frequency of CS3 gene was found to be 0.985 and 0.990 in cases studied and controls respectively. The comparison between cases studied and controls with respect to TfC and CS3 polymorphism was found to be statistically non-significant while the comparison between cases studied and controls for Hp polymorphism was found to be statistically significant (chi 2 = 21.88, p < 0.01).


Asunto(s)
Estudios de Casos y Controles , Complemento C3/genética , Enfermedad Coronaria/genética , Frecuencia de los Genes , Marcadores Genéticos/genética , Predisposición Genética a la Enfermedad/genética , Haptoglobinas/genética , Humanos , India , Infarto del Miocardio/genética , Fenotipo , Polimorfismo Genético , Transferrina/genética
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