Estudo epidemiológico de pacientes internados na unidade de tratamento de queimados do Hospital Geral de Vila Penteado - São Paulo / Epidemiological study of patients hospitalized in the burn care unit of the Vila Penteado General Hospital - São Paulo

Introdução: As queimaduras são lesões de grande morbidade e mortalidade que geram considerável ônus para o estado. Este estudo tem como objetivo traçar o perfil epidemiológico dos pacientes internados na Unidade de Tratamento de Queimados (UTQ) do Hospital Geral de Vila Penteado (HGVP/SP). Método: Foram analisados os dados de internações de pacientes na UTQ do HGVP, no período de Janeiro/2012 a Julho/2013, sendo avaliadas as seguintes variáveis: gênero, idade, causa e extensão da queimadura, intervalo entre queimadura/internação, tempo de internação e evolução do paciente. Resultados: Observou-se predominância das internações em homens (65,8%). Em relação à idade, houve maior concentração de queimados na população adulta (80%). O fogo foi a principal causa de lesões (58,5%), seguido pela escaldadura (19,5%); 62% das queimaduras ocorreram no domicílio e 11,5%, no trabalho. Constatou-se que a maioria das vítimas (56,1%) apresentaram queimaduras de médio e grande porte e que 46,3% dos pacientes foram admitidos nas primeiras 24 horas pós-queimaduras. Quanto ao tempo de internação, foram verificados períodos inferiores a 15 dias como sendo os de maior incidência (55,4%). Obteve-se uma taxa de altas hospitalares igual a 83%, contra uma taxa de óbitos de 17%. Conclusão: Este estudo demonstrou o perfil de queimaduras e internações na UTQ do HGVP compatível com a grande maioria dos dados de outros centros especializados, ressaltando a importância dos estudos epidemiológicos que visam à prevenção desse problema.

Introduction: Burns are injuries with major morbidity and mortality and are a considerable burden on the government. The aim of this study was to investigate the epidemiological profile of patients admitted to the burn care unit (BCU) of the Vila Penteado General Hospital (HGVP/SP). Method: The data analyzed were derived from patient admissions to the BCU of the HGVP, from January 2012 to July 2013, using the following variables: sex, age, cause and extent of the burn, time between burn/admission, estratificalength of stay, and patient's progress. Results: The majority of admissions were observed in men (65.8%). There was a greater percentage of burn patients in the adult population (80%). Fire was the main cause of injury (58.5%), followed by scalding (19.5%); 62% of burns occurred at home and 11.5% at work. Most victims (56.1%) had medium and large burns, and 46.3% of the patients were admitted in the first 24 hours after a burn. A length of stay of less than 15 days was most common (55.4%). The hospital discharge rate was 83% with a death rate of 17%. Conclusion: This study demonstrated that the epidemiological profile for burns and admissions to the BCU of the HGVP was consistent with the great majority of data from other specialty centers, and emphasizes the importance of epidemiological studies on prevention.

Histological modification in TRAM flap in rats treated with pentoxifylline

PURPOSE: To investigate the blood vessels' concentration in TRAM flap's rat model, in the presence of pentoxifylline. METHODS: 32 male, Wistar-EPM rats were divided into two groups. Control group (C): 0.5 ml of saline, intraperitoneally, once a day, for seven days before flap elevation; PTX group (P): pentoxifylline (20mg/kg/day), intraperitoneally, for seven days before flap elevation. After that, they were submitted to a caudal unipedicle TRAM flap. On the fifth postoperative day, percentages of flap necrosis were determined via the "paper template" method and Tram flap's zone IV skin biopsies were taken for histological analysis. RESULTS: the mean percentage of flap necrosis in group C was 58.7 % and in group P, 31.1 (Wilcoxon test; p = 0.003). Mean capillary vessels number in zone IV's skin in C group was 33.4 and in P group was 71.9 (p=0.008). CONCLUSIONS: Pentoxifylline was effective reducing the necrosis in the caudal unipedicle TRAM flap in the rat as well as increasing the number of capillaries in an ischemic zone (zone IV). .