Effect on dose owing to source displacement in coronary endovascular brachytherapy / 中国医学科学院学报

<p><b>OBJECTIVE</b>To investigate the effect on the dose distribution of source position displacement with the target region margin in catheter-based 192Ir line source endovascular brachytherapy.</p><p><b>METHOD</b>Dose rate distribution along longitudinal axes was estimated by the formula recommended by AAPM No.60 and No. 43.</p><p><b>RESULTS</b>In the two cases of source displacement (1.1 and 5 mm) doses of target region margin was decreased dramatically (at most 53.9% and 565.8% respectively) were compared to that of no source displacement, and the affected range was 6 mm and 9 mm respectively.</p><p><b>CONCLUSION</b>Source displacement will lead to the decrease of dose in target region margin.</p>