"Discussion on ""Microcomputer Principle and Interface Technology"" course in military medical university based on SPOC mode" / 医疗卫生装备

Objective To explore the feasibility of applying small private online course (SPOC) in the course of Microcomputer Principle and Interface Technology to solve its problems in complicated knowledge points,abstract contents and difficulty in understanding.Methods The characteristics of the undergraduate students in the military medical university and SPOC mode were analyzed,and then the design and implementation of a SPOC-based Microcomputer Principle and Interface Technology course were explored in the military medical university.Results By applying the SPOC into the teaching of Microcomputer Principle and Interface Technology course,the student could find out the forgotten or leaked knowledge and reiterate them to reinforce the memory of those knowledge points,which promoted their self-regulation of learning.Besides,teaching the students with real cases not only increased the learner's enthusiasm but also strengthened the military medical background.The offline group discussion facilitated the students in understanding and application of knowledge.Conclusion Applying SPOC mode into PMIT teaching no doubt improves the effect and quality of teaching and learning.

Incremental value of 99Tcm-MIBI SPECT/CT imaging on the preoperative diagnosis of primary hyperparathyroidism / 中华核医学与分子影像杂志

Objective To investigate the incremental value of 99Tcm-MIBI SPECT/CT imaging in the preoperative diagnosis of PHPT.Methods Forty-one patients (13 males,28 females,age range:14-82 (50.0± 13.2) years)with PHPT were retrospectively enrolled.99Tcm-MIBI dual-phase planar scan,SPECT/CT imaging,CT and neck ultrasound were performed before surgery.All patients had pathological results.McNemarx2 test was used to compare the detection rates of the four imaging methods.ROI method was applied to calculate the uptake ratio (T/NT) and Pearson correlation analysis was used to evaluate correlation between T/NT and serum intact PTH,Ca,the lesion volume measured after parathyroidectomy.Results A total of 42 parathyroid lesions were confirmed by pathology.There were 39 patients with parathyroid adenoma (2 with double adenomas,and 37 with single adenoma containing 2 ectopic adenomas) and 1 patient with parathyroid carcinoma.The detection rate of planar scan,SPECT/CT imaging,CT and neck ultrasound were 78.0％ (32/41),92.7％ (38/41),73.2％ (30/41) and 70.7％ (29/41) respectively.Detection rate of SPECT/CT imaging was significantly higher than that of planar scan,CT or ultrasonography (x2 =4.17,4.90,5.82,all P＜0.01).However there were no remarkable differences between the detection rate of planar scan and that of CT or ultrasonography (x2=0.08,0.36,both P＞0.05).Detection rates of CT and ultrasonography were not significantly different either (x2 =1.90,P＞0.05).T/NT in delayed planar imaging were significantly correlated with PTH,Ca and the lesion volume measured after parathyroidectomy (r =0.56,0.54,0.56,all P＜0.01).Conclusions Compared with 99Tcm-MIBI dual-phase planar scan,CT and ultrasonography,SPECT/CT imaging could be of important clinical value for preoperative localization of PHPT because of its higher detection rate and accurate anatomical localization ability.

Induction of polyploid hairy roots and its plant regeneration in Pogostemon cablin / 生物工程学报

Abstract: In order to enhance the content of secondary metabolites patchouli alcohol in Pogostemon cablin, we induced polyploid hairy roots and their plant regeneration, and determined the content of patchouli alcohol through artificial chromosome doubling with colchicine. The highest rate of polyploidy induction was more than 40% when hairy roots were treated with 0.05% colchicine for 36 h. The obtained polyploid hairy roots formed adventitious shoots when cultured in an MS medium with 6-BA 0.2 mg/L and NAA 0.1 mg/L for 60 d. Compared with the control diploid plants, the polyploid hairy root-regenerated plants of P. cablin had more developed root systems, thicker stems, shorter internodes and longer, wider and thicker leaves. Observation of the chromosome number in their root tip cells reveals that the obtained polyploid regenerated plants were tetraploidy, with 128 (4n = 128) chromosomes. The leaves contained around twice as many stomatal guard cells and chloroplasts as the controls, but the stomatal density declined with increasing ploidy. The stomatal density in diploid plants was around 1.67 times of that in polyploid plants. GC-MS analysis shows that the content of patchouli alcholol in the hairy root-derived polyploid plants was about 4.25 mg/g dry weight, which was 2.3 times of that in diploid plants. The present study demonstrates that polyploidization of hairy roots can stimulate the content of patchouli alcholol in medicinal plant of P. cablin.

The measurement frequency distribution in tissue impedance spectroscopy measurement / 生物医学工程学杂志

In the research of tissue impedance spectroscopy measurement, the authors constructed a frequency sets that produce angularly equidistant points on the Nyquist loci. The studies of simulation data model demonstrate that, by use of the same quantity of frequency points and in comparison with the frequency sets that are logarithmic and quasi-linear, the angularly equidistant frequency sets can improve the estimate accuracy of tissue electrical model parameters of alpha and fc.

Computer-aided Diagnosis of Bladder Neoplasm by Using Imaging Features / 医疗卫生装备

Objective To provide theoretical evidences for diagnosis of bladder neoplasm by using more information of imaging features. Methods MRI images of bladder neoplasm were collected for this research. The ROI (region of interest) area was selected manually,and noise reduction and sharpening were applied to the ROI area by using LoG (Laplacian of Gaussian) filter. The texture features of bladder neoplasm and normal bladder wall (smooth muscle),such as mean grey-level intensity,entropy,uniformity were calculated. A statistical analysis was made at last. Results The values of texture features were analyzed by t-test. Entropy and uniformity show significant differences between the two groups. But Mean grey-level intensity hasn't indicated this difference. Conclusion This texture features may be applied to decide the invasive depth of bladder neoplasm,it also means that the stage of bladder neoplasm may be fixed by this system.

Simulation study of canceling technology for strong clutters in life detector based on radar / 医疗卫生装备

Strong clutters are produced by the echo waves from the debris when the life detector based on radar locates the living human subject under the debris, which makes the life detector work abnormally because the amplifier is saturate. A canceling technology for the strong clutters is provided to solve the problems discussed above in this paper. The canceling technology for the strong clutters can provide methods and theories in practice by constructing and simulating the mathematic model in the computer, analyzing and discussing the results.

Knowledge expression system and its application to medical diagnosis computer-aided system / 医疗卫生装备

The attention is often paid toknowledge processing procedure including knowledge acquisition,knowledge expression and knowledge utilization when expert system is studied and designed.The knowledge expression is the most basic topic among them.Knowledge expression system and its application tomedical diagnosis computer-aided system are discussed in this paper.

Research of effect of stray capacitance on measurement accuracy in tissue impedance spectroscopy measurement / 医疗卫生装备

In the tissue impedance spectroscopy measurements ,four-electrode method are normally used. A measurement error caused by stray capacitance between lines of drive electrode and receive electrode is not a trivial problem. This paper studied this error and reached the results This stray capacitance introduces errors which increase with frequency and has more effect on the imaginary part than on the real part in the measurement frequency range.

Design of impedance spectroscopy database frame based on ADD Technique / 医疗卫生装备

The author uses the database technique to manage the impedance spectroscopy data.In design of impedance spectroscopy database frame,ActiveX Data Object(ADO)technique is adopted to improve the agility and efficiency.It also enhances the efficiency to use data binding technique to avoid complex data type transformation in appending and amending.