RESUMEN
Multiple myeloma is the most common type of malignant hemopathy, affecting mainly the elderly; the occurrence in adolescents and young adults remains exceptional. This is a 5-year retrospective study conducted at the Hematology Laboratory of the CHU Hassan II in Fez, including 13 patients with multiple myeloma whose age is less than or equal to 40 years. The average age of patients is 35.5 years, with a male predominance. The clinical signs are dominated by bone signs. The biological assessment shows a monoclonal gamma peak in 60% of cases, and renal failure in 38% of cases. Sternal puncture showed plasma cell infiltration in 30% of cases. 45% of the patients were treated by CDT, 55% by VDT, with good progress in 30% of cases over an average of 60 months. This study shows that myeloma in young people is marked by its clinical severity, but the therapeutic advances made it possible to improve the prognosis of the patients