[Kikuchi disease and systemic lupus erythematosus]

Kikuchi's disease or histiocytic necrotizing lymphadenitis is a rare anatomico-clinical entity affecting young females. It is clinically manifested by generalized lymphadenopathy, fever and neutropenia. Diagnosis depends on histological examination. The etiology is not well known yet, although an autoimmune hypothesis has been suggested. It may be associated with systemic lupus erythematosus. The authors reported a case of Kikuchi's disease associated with apparition of secondary systemic lupus erythematosus. It is about a 16 years old woman who presented with fever, generalized lymphadenopathy, inflammatory polyarthritis and myalgia. Laboratory tests revealed an important inflammatory syndrome with leucopenia. Immunological test were normal and lymph node biopsy was in favour of necrotizing histiocytic lymphadenitis. [Kikuchi disease]. Later on after one year lupus disease was finally identified. Kikuchi's disease is a rare less frequent benign condition, the clinical symptoms resolve spontaneously but a regular Follow up should be taken with these patients to detect secondary onset of another autoimmune disease especially the systemic lupus erythematosus

Myeloradiculonevritee et cryoglobulinemie au cours d' une leishmaniose visceral de l'adulte

Visceral leishmaniasis is a severe parasitic inffection that affects the child but rarely the immunocompetent adult. The authors report the case of a patient 35 years old, native of south Morocco and who presented with visceral leishmaniasis with a cryoglobulinemia and myeloradiculoneuritis a rare neurologic affection confirmed by electromyogram. The diagnosis has been suspected in the presence of pancytopenia and a feverish hepatosplenomegaly. The confirmation has been based on the leishmanial serology and the visualization of the leishmaniq in the sternal osteomedullary biopsy puncture. The evolution has been excellent under glaucantine N-Methyl associated with corticotherapy